Stimulation of autophagy by the p53 target gene Sestrin2.
about
Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell deathSestrins at the crossroad between stress and agingBlue-Print Autophagy: Potential for Cancer TreatmentAdvances in Autophagy Regulatory MechanismsPeptidylarginine deiminases in citrullination, gene regulation, health and pathogenesisThe role of tumor suppressor p53 in the antioxidant defense and metabolismSustained proliferation in cancer: Mechanisms and novel therapeutic targetsp53 Regulates oxidative stress-mediated retrograde signaling: a novel mechanism for chemotherapy-induced cardiac injuryInteraction of OKL38 and p53 in regulating mitochondrial structure and functionThe inhibition of autophagy sensitises colon cancer cells with wild-type p53 but not mutant p53 to topotecan treatmentMaintenance of metabolic homeostasis by Sestrin2 and Sestrin3Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cellsSestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injuryDNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescenceAnticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity.Antitumor agent 25-epi Ritterostatin GN1N induces endoplasmic reticulum stress and autophagy mediated cell death in melanoma cellsEffects of Gui Zhu Yi Kun formula on the P53/AMPK pathway of autophagy in granulosa cells of rats with polycystic ovary syndrome.Detection of WIPI1 mRNA as an indicator of autophagosome formationA low-carb diet kills tumor cells with a mutant p53 tumor suppressor gene: the Atkins diet suppresses tumor growthSestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells.p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis.Sestrins orchestrate cellular metabolism to attenuate aging.A curated census of autophagy-modulating proteins and small molecules: candidate targets for cancer therapy.Serum starvation induces DRAM expression in liver cancer cells via histone modifications within its promoter locusDepending on the stage of hepatosteatosis, p53 causes apoptosis primarily through either DRAM-induced autophagy or BAX.Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart.p53, aerobic metabolism, and cancer.Autophagy regulation in cancer development and therapy.Autophagy in tumor suppression and cancer therapy.Autophagy as a therapeutic target in cancer.Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathyThe Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.Autophagy and cell growth--the yin and yang of nutrient responses.MicroRNA‑34a induces apoptosis in PC12 cells by reducing B‑cell lymphoma 2 and sirtuin‑1 expression.Time Course Analysis of Skeletal Muscle Pathology of GDE5 Transgenic Mouse.Pathophysiology of protein aggregation and extended phenotyping in filaminopathy.The Retinoblastoma Tumor Suppressor Protein (pRb)/E2 Promoter Binding Factor 1 (E2F1) Pathway as a Novel Mediator of TGFβ-induced Autophagy.
P2860
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P2860
Stimulation of autophagy by the p53 target gene Sestrin2.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Stimulation of autophagy by the p53 target gene Sestrin2.
@en
Stimulation of autophagy by the p53 target gene Sestrin2.
@nl
type
label
Stimulation of autophagy by the p53 target gene Sestrin2.
@en
Stimulation of autophagy by the p53 target gene Sestrin2.
@nl
prefLabel
Stimulation of autophagy by the p53 target gene Sestrin2.
@en
Stimulation of autophagy by the p53 target gene Sestrin2.
@nl
P2093
P50
P356
P1433
P1476
Stimulation of autophagy by the p53 target gene Sestrin2.
@en
P2093
Alfredo Criollo
Eugenia Morselli
Pierre-Luc Mouchel
Rosa Carnuccio
P304
P356
10.4161/CC.8.10.8498
P577
2009-05-20T00:00:00Z