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Using measures of single-cell physiology and physiological state to understand organismic agingUnrevealed mosaicism in the next-generation sequencing eraSomatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesisIntra-organ variation in age-related mutation accumulation in the mouse.Effect of Ku80 deficiency on mutation frequencies and spectra at a LacZ reporter locus in mouse tissues and cellsAge- and temperature-dependent somatic mutation accumulation in Drosophila melanogasterRegulation of Drosophila Lifespan by bellwether Promoter Alleles.Age-related somatic mutations in the cancer genomeDo DNA Double-Strand Breaks Drive Aging?Genome instability, cancer and aging.Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expressionDirect mutation analysis by high-throughput sequencing: from germline to low-abundant, somatic variantsLoss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila.5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1.The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin FibroblastsNAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1.Age-dependent variability in gene expression in male Fischer 344 rat retina.Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?Genome instability: cancer or aging?Measuring genome instability in aging - a mini-review.A molecular mechanism of chronological aging in yeast.Age-associated alterations in the somatic mutation and DNA methylation levels in plants.A genetic analysis of nitric oxide-mediated signaling during chronological aging in the yeast.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Genome dynamics in aging mice.
@en
Genome dynamics in aging mice.
@nl
type
label
Genome dynamics in aging mice.
@en
Genome dynamics in aging mice.
@nl
prefLabel
Genome dynamics in aging mice.
@en
Genome dynamics in aging mice.
@nl
P2860
P356
P1433
P1476
Genome dynamics in aging mice.
@en
P2093
Martijn E T Dollé
P2860
P304
P356
10.1101/GR.125502
P577
2002-11-01T00:00:00Z