Serum pharmacokinetics and cerebrospinal fluid concentration analysis of the new IgG4 monoclonal antibody GNbAC1 to treat multiple sclerosis: A Phase 1 study.

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Immunoglobulin G; structure and functional implications of different subclass modifications in initiation and resolution of allergy.HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity.

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Serum pharmacokinetics and cerebrospinal fluid concentration analysis of the new IgG4 monoclonal antibody GNbAC1 to treat multiple sclerosis: A Phase 1 study.

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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Serum pharmacokinetics and cer ...... le sclerosis: A Phase 1 study.

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Serum pharmacokinetics and cer ...... le sclerosis: A Phase 1 study.

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Serum pharmacokinetics and cer ...... le sclerosis: A Phase 1 study.

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Serum pharmacokinetics and cer ...... le sclerosis: A Phase 1 study.

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Serum pharmacokinetics and cer ...... le sclerosis: A Phase 1 study.

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Serum pharmacokinetics and cer ...... le sclerosis: A Phase 1 study.

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Alois B Lang

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Arno Kromminga

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Corinne Bernard

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François Curtin

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Hervé Porchet

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Virginie Vidal

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P2860

Persistent endothelial abnormalities and blood-brain barrier leak in primary and secondary progressive multiple sclerosis

Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033

Immunologic monitoring during a phase 2a trial of the GNbAC1 antibody in patients with MS.

Preclinical and early clinical development of GNbAC1, a humanized IgG4 monoclonal antibody targeting endogenous retroviral MSRV-Env protein.

Clinical pharmacokinetics of therapeutic monoclonal antibodies.

Monoclonal antibody therapy in multiple sclerosis: critical appraisal and new perspectives.

Novel and imminently emerging treatments in relapsing-remitting multiple sclerosis.

GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus: a first-in-humans randomized clinical study.

A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-up.

A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients.

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854-860

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10.1080/19420862.2016.1168956

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cerebrospinal fluid

multiple sclerosis

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4968100

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Serum pharmacokinetics and cerebrospinal fluid concentration analysis of the new IgG4 monoclonal antibody GNbAC1 to treat multiple sclerosis: A Phase 1 study.

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P2860

P2860

Serum pharmacokinetics and cerebrospinal fluid concentration analysis of the new IgG4 monoclonal antibody GNbAC1 to treat multiple sclerosis: A Phase 1 study.

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