Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.
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Anaplastic lymphoma kinase: signalling in development and diseaseCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyAberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsTargeting Hedgehog--a cancer stem cell pathwayActivation of the sonic hedgehog signaling controls human pulmonary arterial smooth muscle cell proliferation in response to hypoxiaThe controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.Identification of anaplastic lymphoma kinase as a potential therapeutic target in Basal Cell CarcinomaGlioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma.Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma.Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.Loss of TCR-beta F1 and/or EZRIN expression is associated with unfavorable prognosis in nodal peripheral T-cell lymphomas.Transcriptional regulation of serine/threonine protein kinase (AKT) genes by glioma-associated oncogene homolog 1.Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphomaNew developments in the pathology of malignant lymphoma: a review of the literature published from January to August 2009.Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer.The utility of hedgehog signaling pathway inhibition for cancer.Anaplastic lymphoma kinase as a therapeutic target.New prospects for drug development: the hedgehog pathway revealed. Focus on hematologic malignancies.ALK-positive cancer: still a growing entity.Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma: current and future perspectives in adult and paediatric disease.New insight into hedgehog signaling in hematological malignancies.Hedgehog signaling in cancer stem cells: a focus on hematological cancers.Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes.An update of ALK inhibitors in human clinical trials.GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML.The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met.Protein arginine methyltransferase 1 interacts with Gli1 and regulates its transcriptional activity.Therapeutic target discovery and drug development in cancer stem cells for leukemia and lymphoma: from bench to the clinic.The clinicopathological significance and relationship of Gli1, MDM2 and p53 expression in resectable pancreatic cancer.Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development.The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma.GSK3-SCF(FBXW7) targets JunB for degradation in G2 to preserve chromatid cohesion before anaphase.Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue.Essential role of TAK1 in regulating mantle cell lymphoma survival.Smoothened as a new therapeutic target for human osteosarcoma.Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.Inhibition of p70S6K2 down-regulates Hedgehog/GLI pathway in non-small cell lung cancer cell linesPI3K-AKT signaling is a downstream effector of retinoid prevention of murine basal cell carcinogenesis.Pediatric T- and NK-cell lymphomas: new biologic insights and treatment strategies.
P2860
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P2860
Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Sonic hedgehog signaling pathw ...... naplastic large cell lymphoma.
@en
Sonic hedgehog signaling pathw ...... naplastic large cell lymphoma.
@nl
type
label
Sonic hedgehog signaling pathw ...... naplastic large cell lymphoma.
@en
Sonic hedgehog signaling pathw ...... naplastic large cell lymphoma.
@nl
prefLabel
Sonic hedgehog signaling pathw ...... naplastic large cell lymphoma.
@en
Sonic hedgehog signaling pathw ...... naplastic large cell lymphoma.
@nl
P2093
P1433
P1476
Sonic hedgehog signaling pathw ...... anaplastic large cell lymphoma
@en
P2093
Cristiane Milito
Elias Drakos
Fatan Kasbidi
Jeong Hee Cho-Vega
L Jeffrey Medeiros
Patrick A Lennon
Rajesh R Singh
Rajyalakshmi Luthra
Shuguang Ma
Yogesh Davuluri
P304
P356
10.1158/0008-5472.CAN-08-1808
P407
P577
2009-02-24T00:00:00Z