From the Gla domain to a novel small-molecule detector of apoptosis.
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Imaging radiation response in tumor and normal tissue.Biomarkers and molecular probes for cell death imaging and targeted therapeuticsPreclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomographyPreclinical Evaluation of 18F-ML-10 to Determine Timing of Apoptotic Response to Chemotherapy in Solid TumorsRadioiodinated phenylalkyl malonic acid derivatives as pH-sensitive SPECT tracers.Applications of molecular imaging.Development of radiotracers for oncology--the interface with pharmacologyMolecular PET Imaging of Cyclophosphamide Induced Apoptosis with 18F-ML-8Radiolabeled isatin binding to caspase-3 activation induced by anti-Fas antibody.Synthesis of ApoSense compound [18F]2-(5-(dimethylamino)naphthalene-1-sulfonamido)-2-(fluoromethyl)butanoic acid ([18F]NST732) by nucleophilic ring opening of an aziridine precursor.A Systematic Comparison of 18F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment.Characterization of [(99m)Tc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis.Imaging caspase-3 activation as a marker of apoptosis-targeted treatment response in cancer.The preclinical study of predicting radiosensitivity in human nasopharyngeal carcinoma xenografts by 18F-ML-10 animal- PET/CT imaging.Optimization of Early Response Monitoring and Prediction of Cancer Antiangiogenesis Therapy via Noninvasive PET Molecular Imaging Strategies of Multifactorial BioparametersA HSP60-targeting peptide for cell apoptosis imaging.First use of (18)F-labeled ML-10 PET to assess apoptosis change in a newly diagnosed glioblastoma multiforme patient before and early after therapy.Challenges and Approaches to Quantitative Therapy Response Assessment in Glioblastoma Multiforme Using the Novel Apoptosis Positron Emission Tomography Tracer F-18 ML-10.SPECT and PET radiopharmaceuticals for molecular imaging of apoptosis: from bench to clinicClinical applications in molecular imaging.New frontiers in the design and synthesis of imaging probes for PET oncology: current challenges and future directions.Application of microPET imaging approaches in the study of pediatric anesthetic-induced neuronal toxicity.The slow cell death response when screening chemotherapeutic agentsIn vitro and in vivo evaluation of the caspase-3 substrate-based radiotracer [(18)F]-CP18 for PET imaging of apoptosis in tumors.In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probe.A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkersFluorescent light-up probe with aggregation-induced emission characteristics for in vivo imaging of cell apoptosis.Automated radiosynthesis of [(18)F]ML-10, a PET radiotracer dedicated to apoptosis imaging, on a TRACERLab FX-FN module.Microfluidic radiosynthesis and biodistribution of [18 F] 2-(5-fluoro-pentyl)-2-methyl malonic acid.The development of an indirect competitive immunomagnetic-proximity ligation assay for small-molecule detection.In Vivo Evaluation of Radiofluorinated Caspase-3/7 Inhibitors as Radiotracers for Apoptosis Imaging and Comparison with [18F]ML-10 in a Stroke Model in the Rat.MicroPET imaging of ketamine-induced neuronal apoptosis with radiolabeled DFNSH.Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with ¹⁸F-ML-10.Positron emission tomography imaging of cell death with [(18)F]FPDuramycin.Use of LC-MS for the quality control of radiopharmaceuticals: example of [(18)F]ML10.A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc03207e.Radiolabeled apoptosis imaging agents for early detection of response to therapy
P2860
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P2860
From the Gla domain to a novel small-molecule detector of apoptosis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
From the Gla domain to a novel small-molecule detector of apoptosis.
@en
From the Gla domain to a novel small-molecule detector of apoptosis.
@nl
type
label
From the Gla domain to a novel small-molecule detector of apoptosis.
@en
From the Gla domain to a novel small-molecule detector of apoptosis.
@nl
prefLabel
From the Gla domain to a novel small-molecule detector of apoptosis.
@en
From the Gla domain to a novel small-molecule detector of apoptosis.
@nl
P2093
P2860
P356
P1433
P1476
From the Gla domain to a novel small-molecule detector of apoptosis.
@en
P2093
Anat Shirvan
Ayelet Reshef
Galit Levin
Hagit Grimberg
P2860
P2888
P304
P356
10.1038/CR.2009.17
P577
2009-05-01T00:00:00Z
P5875
P6179
1046425999