Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
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Store-independent activation of Orai1 by SPCA2 in mammary tumorsMigrastatin analogues target fascin to block tumour metastasisSTIM proteins: dynamic calcium signal transducersThe heterogeneity of store-operated calcium entry in melanomaAltered expression of stromal interaction molecule (STIM)-calcium release-activated calcium channel protein (ORAI) and inositol 1,4,5-trisphosphate receptors (IP3Rs) in cancer: will they become a new battlefield for oncotherapy?SOCE and cancer: Recent progress and new perspectivesThe Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and ProgressionEmerging role of TRP channels in cell migration: from tumor vascularization to metastasisIon channels and transporters in tumour cell migration and invasionCalcium influx pathways in breast cancer: opportunities for pharmacological interventionNon-stimulated, agonist-stimulated and store-operated Ca2+ influx in MDA-MB-468 breast cancer cells and the effect of EGF-induced EMT on calcium entryTRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and ContractilityCa2+/H+ exchange by acidic organelles regulates cell migration in vivo.The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin.Store-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migrationThe calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells.The STIM1-Orai1 pathway of store-operated Ca2+ entry controls the checkpoint in cell cycle G1/S transition.TRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin CortexChemokines, selectins and intracellular calcium flux: temporal and spatial cues for leukocyte arrestStore-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patientsStanniocalcin 2 is a negative modulator of store-operated calcium entryRegulation of podosome formation, microglial migration and invasion by Ca(2+)-signaling molecules expressed in podosomesSTIMulating store-operated Ca(2+) entry.Migrational guidance of neutrophils is mechanotransduced via high-affinity LFA-1 and calcium fluxMolecular mechanisms of spontaneous and directed mast cell motility.Role of molecular determinants of store-operated Ca(2+) entry (Orai1, phospholipase A2 group 6, and STIM1) in focal adhesion formation and cell migration.hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+ entry and calpain 2Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependentSTIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion.Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma.Regulation of membrane ruffling by polarized STIM1 and ORAI1 in cortactin-rich domains.MTI-101 treatment inducing activation of Stim1 and TRPC1 expression is a determinant of response in multiple myeloma.Overexpression of stromal interaction molecule 1 may promote epithelial‑mesenchymal transition and indicate poor prognosis in gastric cancerNFAT proteins: emerging roles in cancer progression.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.A novel native store-operated calcium channel encoded by Orai3: selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells.The TRPC channel blocker SKF 96365 inhibits glioblastoma cell growth by enhancing reverse mode of the Na(+) /Ca(2+) exchanger and increasing intracellular Ca(2+).Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinomaStore-operated Ca2+ entry does not control proliferation in primary cultures of human metastatic renal cellular carcinoma.Remodeling of purinergic receptor-mediated Ca2+ signaling as a consequence of EGF-induced epithelial-mesenchymal transition in breast cancer cells
P2860
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P2860
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
@en
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
@nl
type
label
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
@en
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
@nl
prefLabel
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
@en
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
@nl
P2093
P1433
P1476
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis.
@en
P2093
J Jillian Zhang
Shengyu Yang
Xin-Yun Huang
P304
P356
10.1016/J.CCR.2008.12.019
P577
2009-02-01T00:00:00Z