New class of competitive inhibitor of bacterial histidine kinases.
about
Challenges of antibacterial discoveryThiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis.Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence.Inactivation of multiple bacterial histidine kinases by targeting the ATP-binding domain.Development and validation of a high-throughput cell-based screen to identify activators of a bacterial two-component signal transduction system.Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.Sensor histidine kinase is a β-lactam receptor and induces resistance to β-lactam antibiotics.The Rational Design, Synthesis, and Antimicrobial Properties of Thiophene Derivatives That Inhibit Bacterial Histidine Kinases.The CiaRH system of Streptococcus pneumoniae prevents lysis during stress induced by treatment with cell wall inhibitors and by mutations in pbp2x involved in beta-lactam resistance.Essentiality, bypass, and targeting of the YycFG (VicRK) two-component regulatory system in gram-positive bacteria.Mechanistic insight into inhibition of two-component system signaling.Essential Two-Component Systems Regulating Cell Envelope Functions: Opportunities for Novel Antibiotic Therapies.
P2860
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P2860
New class of competitive inhibitor of bacterial histidine kinases.
description
2005 nî lūn-bûn
@nan
2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
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2005年學術文章
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name
New class of competitive inhibitor of bacterial histidine kinases.
@en
New class of competitive inhibitor of bacterial histidine kinases.
@nl
type
label
New class of competitive inhibitor of bacterial histidine kinases.
@en
New class of competitive inhibitor of bacterial histidine kinases.
@nl
prefLabel
New class of competitive inhibitor of bacterial histidine kinases.
@en
New class of competitive inhibitor of bacterial histidine kinases.
@nl
P2093
P2860
P1476
New class of competitive inhibitor of bacterial histidine kinases.
@en
P2093
Anna Riley
J Estelle Foster
Jonathan R McClain
Kenneth Henry
Malcolm E Winkler
Pei-Ming Sun
Raymond Gilmour
Thalia I Nicas
P2860
P304
P356
10.1128/JB.187.23.8196-8200.2005
P577
2005-12-01T00:00:00Z