Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1alpha levels contribute to emergence of an aggressive phenotype in prostate cancer.
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Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cellsPhenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironmentLoss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38.p38α MAPK is required for arsenic-induced cell transformationProstate cancer cell lines under hypoxia exhibit greater stem-like properties.Microtubular stability affects pVHL-mediated regulation of HIF-1alpha via the p38/MAPK pathway in hypoxic cardiomyocytes.Impact of hypoxia on the metastatic potential of human prostate cancer cells.A protein therapeutic modality founded on molecular regulation.Dual targeting of the androgen receptor and hypoxia-inducible factor 1α pathways synergistically inhibits castration-resistant prostate cancer cells.Pro-life role for c-Jun N-terminal kinase and p38 mitogen-activated protein kinase at rostral ventrolateral medulla in experimental brain stem deathPhosphorylated-p38 mitogen-activated protein kinase expression is associated with clinical factors in invasive breast cancer.Role of p38 MAP Kinase Signal Transduction in Solid TumorsAssociations of proteins relevant to MAPK signaling pathway (p38MAPK-1,HIF-1 and HO-1) with coronary lesion characteristics and prognosis of peri-menopausal women.To die or to survive, a fatal question for the destiny of prostate cancer cells after androgen deprivation therapy.The nrf1 and nrf2 balance in oxidative stress regulation and androgen signaling in prostate cancer cells.MAP Kinases and Prostate Cancer.Hypoxia enhances the expression of prostate-specific antigen by modifying the quantity and catalytic activity of Jumonji C domain-containing histone demethylases.Hypoxia-induced up-regulation of aquaporin-1 protein in prostate cancer cells in a p38-dependent manner.Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells.Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell propertiesPaeoniflorin inhibits proliferation of endometrial cancer cells via activating MAPK and NF-κB signaling pathways.Phosphodiesterase type 5 and cancers: progress and challenges.Epidermal growth factor induces p38 MAPK-dependent G0/G1-to-S transition in prostate cancer cells upon androgen deprivation conditions.Eukaryotic Translation Initiation Factor 4 Gamma 1 (eIF4G1) is upregulated during Prostate cancer progression and modulates cell growth and metastasis.CD40-mediated HIF-1α expression underlying microangiopathy in diabetic nerve pathology.
P2860
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P2860
Hypoxia-associated p38 mitogen-activated protein kinase-mediated androgen receptor activation and increased HIF-1alpha levels contribute to emergence of an aggressive phenotype in prostate cancer.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
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2009年学术文章
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2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
Hypoxia-associated p38 mitogen ...... phenotype in prostate cancer.
@en
Hypoxia-associated p38 mitogen ...... phenotype in prostate cancer.
@nl
type
label
Hypoxia-associated p38 mitogen ...... phenotype in prostate cancer.
@en
Hypoxia-associated p38 mitogen ...... phenotype in prostate cancer.
@nl
prefLabel
Hypoxia-associated p38 mitogen ...... phenotype in prostate cancer.
@en
Hypoxia-associated p38 mitogen ...... phenotype in prostate cancer.
@nl
P2093
P2860
P356
P1433
P1476
Hypoxia-associated p38 mitogen ...... phenotype in prostate cancer.
@en
P2093
L Khandrika
R B Meacham
R Chandhoke
R Lieberman
P2860
P2888
P304
P356
10.1038/ONC.2008.476
P407
P577
2009-01-19T00:00:00Z