A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
about
Cloning of the Candida albicans homolog of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in beta-1,3-glucan synthesisLoss of the plasma membrane-bound protein Gas1p in Saccharomyces cerevisiae results in the release of beta1,3-glucan into the medium and induces a compensation mechanism to ensure cell wall integrity.Multiple copies of PBS2, MHP1 or LRE1 produce glucanase resistance and other cell wall effects in Saccharomyces cerevisiae.In vitro activity of 1,3-beta-D-glucan synthase requires the GTP-binding protein Rho1.A spheroplast rate assay for determination of cell wall integrity in yeast.The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase.Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase.HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiaeMolecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiaeDiscovery of novel antifungal (1,3)-beta-D-glucan synthase inhibitorsOverexpression of Sbe2p, a Golgi protein, results in resistance to caspofungin in Saccharomyces cerevisiae.A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds.Photoaffinity analog of the semisynthetic echinocandin LY303366: identification of echinocandin targets in Candida albicansOropharyngeal candidiasis in the era of antiretroviral therapyCaspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis.Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.The spheroplast lysis assay for yeast in microtiter plate format.Antifungal agents: chemotherapeutic targets and immunologic strategies.Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibilityNew methods to assess susceptibilities of Aspergillus isolates to caspofungin.Micafungin in the treatment of invasive candidiasis and invasive aspergillosisIdentification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors.The GTP-binding protein Rho1p is required for cell cycle progression and polarization of the yeast cell.Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies.Papulacandin B resistance in budding and fission yeasts: isolation and characterization of a gene involved in (1,3)beta-D-glucan synthesis in Saccharomyces cerevisiae.Chitin synthase III: synthetic lethal mutants and "stress related" chitin synthesis that bypasses the CSD3/CHS6 localization pathway.Elevated cell wall chitin in Candida albicans confers echinocandin resistance in vivo.Comparative evaluation of Etest and sensititre yeastone panels against the Clinical and Laboratory Standards Institute M27-A2 reference broth microdilution method for testing Candida susceptibility to seven antifungal agentsGenomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature.An update on antifungal targets and mechanisms of resistance in Candida albicans.Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase.Nikkomycin Z supersensitivity of an echinocandin-resistant mutant of Saccharomyces cerevisiaeCharacterization of cwl1+, a gene from Schizosaccharomyces pombe whose overexpression causes cell lysis.Resistance to echinocandin-class antifungal drugs.Development of caspofungin resistance following prolonged therapy for invasive candidiasis secondary to Candida glabrata infection.Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistanceChitinases in Pneumocystis carinii pneumoniaAntifungal drug resistance of oral fungi.The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.Decreased accumulation or increased isoleucyl-tRNA synthetase activity confers resistance to the cyclic beta-amino acid BAY 10-8888 in Candida albicans and Candida tropicalis.
P2860
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P2860
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
@en
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
@nl
type
label
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
@en
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
@nl
prefLabel
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
@en
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
@nl
P2093
P2860
P1476
A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase.
@en
P2093
P2860
P304
P356
10.1128/JB.176.18.5686-5696.1994
P577
1994-09-01T00:00:00Z