Down-modulation of keratin 8 phosphorylation levels by PRL-3 contributes to colorectal carcinoma progression.
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Phosphorylation and Reorganization of Keratin Networks: Implications for Carcinogenesis and Epithelial Mesenchymal TransitionNetworking galore: intermediate filaments and cell migrationAntibody Array Revealed PRL-3 Affects Protein Phosphorylation and Cytokine SecretionPlakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasisInvestigational inhibitors of PTP4A3 phosphatase as antineoplastic agents.Intermediate filament reorganization dynamically influences cancer cell alignment and migration.Keratin 8 expression in colon cancer associates with low faecal butyrate levels.Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancerPRL-3 promotes telomere deprotection and chromosomal instability.PRL-3 and E-cadherin show mutual interactions and participate in lymph node metastasis formation in gastric cancerLoss of keratin 8 phosphorylation leads to increased tumor progression and correlates with clinico-pathological parameters of OSCC patients.Phosphatase of regenerating liver-3 directly interacts with integrin β1 and regulates its phosphorylation at tyrosine 783Keratins in health and cancer: more than mere epithelial cell markersA genome-wide survey over the ChIP-on-chip identified androgen receptor-binding genomic regions identifies a novel prostate cancer susceptibility locus at 12q13.13.miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer.Phosphatase of regenerating liver-3 inhibits invasiveness and proliferation in non-small cell lung cancer by regulating the epithelial-mesenchymal transition.Identification of proteins suppressing the functions of oncogenic phosphatase of regenerating liver 1 and 3.PRL-3 phosphatase and cancer metastasis.Molecular mechanisms of the PRL phosphatases.Keratins in colorectal epithelial function and disease.Quantitative phosphoproteomic analysis reveals system-wide signaling pathways regulated by site-specific phosphorylation of Keratin-8 in skin squamous cell carcinoma derived cell line.Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration.p120-catenin down-regulation and epidermal growth factor receptor overexpression results in a transformed epithelium that mimics esophageal squamous cell carcinomaInflammation decreases keratin level in ulcerative colitis; inadequate restoration associates with increased risk of colitis-associated cancer.Parkin induces upregulation of 40S ribosomal protein SA and posttranslational modification of cytokeratins 8 and 18 in human cervical cancer cells.
P2860
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P2860
Down-modulation of keratin 8 phosphorylation levels by PRL-3 contributes to colorectal carcinoma progression.
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
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2009年學術文章
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2009年學術文章
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name
Down-modulation of keratin 8 p ...... orectal carcinoma progression.
@en
Down-modulation of keratin 8 p ...... orectal carcinoma progression.
@nl
type
label
Down-modulation of keratin 8 p ...... orectal carcinoma progression.
@en
Down-modulation of keratin 8 p ...... orectal carcinoma progression.
@nl
prefLabel
Down-modulation of keratin 8 p ...... orectal carcinoma progression.
@en
Down-modulation of keratin 8 p ...... orectal carcinoma progression.
@nl
P2093
P356
P1476
Down-modulation of keratin 8 p ...... orectal carcinoma progression.
@en
P2093
Eri Mizuuchi
Hiroshi Yokozaki
Shuho Semba
Yoshinori Kodama
P304
P356
10.1002/IJC.24111
P577
2009-04-01T00:00:00Z