Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1.
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Inhibition of Akt/mTOR signaling by the dietary flavonoid fisetinRecent updates of precision therapy for gastric cancer: Towards optimal tailored managementCXCR4 in breast cancer: oncogenic role and therapeutic targetingMolecular targeted approaches to cancer therapy and prevention using chalconesEffect of Low Molecular Weight Heparins (LMWHs) on antiphospholipid Antibodies (aPL)-mediated inhibition of endometrial angiogenesisProtein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiationButein suppresses breast cancer growth by reducing a production of intracellular reactive oxygen speciesElevated postinjury thrombospondin 1-CD47 triggering aids differentiation of patients' defective inflammatory CD1a+dendritic cells.The role of chalcones in suppression of NF-κB-mediated inflammation and cancer.Dietary chalcones with chemopreventive and chemotherapeutic potential.The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway.Dihydroxypentamethoxyflavone down-regulates constitutive and inducible signal transducers and activators of transcription-3 through the induction of tyrosine phosphatase SHP-1Butein, a tetrahydroxychalcone, suppresses cancer-induced osteoclastogenesis through inhibition of receptor activator of nuclear factor-kappaB ligand signalingA STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations.Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network.Butein induces apoptosis and inhibits prostate tumor growth in vitro and in vivo.Coffee polyphenols change the expression of STAT5B and ATF-2 modifying cyclin D1 levels in cancer cellsCancer and diet: How are they related?Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody.Butein is a novel anti-adipogenic compound.Decursin and Doxorubicin Are in Synergy for the Induction of Apoptosis via STAT3 and/or mTOR Pathways in Human Multiple Myeloma Cells.Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells.Targeting erythropoietin for chronic neurodegenerative diseases.An update on antitumor activity of naturally occurring chalcones.Dietary phytochemicals alter epigenetic events and signaling pathways for inhibition of metastasis cascade: phytoblockers of metastasis cascade.New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-κB transcription factors.Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells.Loss of function mutations in PTPN6 promote STAT3 deregulation via JAK3 kinase in diffuse large B-cell lymphoma.STAT3 targeting by polyphenols: Novel therapeutic strategy for melanoma.Butein induces apoptosis in human uveal melanoma cells through mitochondrial apoptosis pathway.Signal transducer and activator of transcription 3 pathway mediates genipin-induced apoptosis in U266 multiple myeloma cells.Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells.The roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis.Apoptosis induction by alantolactone in breast cancer MDA-MB-231 cells through reactive oxygen species-mediated mitochondrion-dependent pathway.Phosphorylation of NTRK1 at Y674/Y675 induced by TP53-dependent repression of PTPN6 expression: a potential novel prognostic marker for breast cancer.RFX-1-dependent activation of SHP-1 inhibits STAT3 signaling in hepatocellular carcinoma cells.SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress.Protein tyrosine phosphatase 1B is a regulator of the interleukin-10-induced transcriptional program in macrophages.Butein activates p53 in hepatocellular carcinoma cells via blocking MDM2-mediated ubiquitination.The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
P2860
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P2860
Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Butein suppresses constitutive ...... in tyrosine phosphatase SHP-1.
@en
Butein suppresses constitutive ...... and activator of transcription
@nl
type
label
Butein suppresses constitutive ...... in tyrosine phosphatase SHP-1.
@en
Butein suppresses constitutive ...... and activator of transcription
@nl
prefLabel
Butein suppresses constitutive ...... in tyrosine phosphatase SHP-1.
@en
Butein suppresses constitutive ...... and activator of transcription
@nl
P2093
P2860
P356
P1476
Butein suppresses constitutive ...... in tyrosine phosphatase SHP-1.
@en
P2093
Bharat B Aggarwal
Bokyung Sung
Kwang Seok Ahn
Manoj K Pandey
P2860
P304
P356
10.1124/MOL.108.052548
P577
2008-12-22T00:00:00Z