Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.
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Targeting the insulin growth factor receptor 1Obesity and cancer, a case for insulin signalingUnderstanding the Key to Targeting the IGF Axis in Cancer: A Biomarker AssessmentCross-Talk between Adiponectin and IGF-IR in Breast CancerThe integrative role of leptin, oestrogen and the insulin family in obesity-associated breast cancer: potential effects of exercisePhosphatidylinositol 3-kinase and antiestrogen resistance in breast cancerDiabetes and cancer: a consensus report.Reducing the Risk of Breast Cancer Recurrence: an Evaluation of the Effects and Mechanisms of Diet and ExerciseThe Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsBRCA1 and Oxidative StressCarcinogenic effects of oil dispersants: a KEGG pathway-based RNA-seq study of human airway epithelial cellsThe insulin-like growth factor-I receptor (IGF-IR) in breast cancer: biology and treatment strategies.Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2)RSK in tumorigenesis: connections to steroid signaling.Body mass index, diabetes, and triple-negative breast cancer prognosis.Exploiting polypharmacology for drug target deconvolutionInhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.Activation of the Akt-mTOR pathway and receptor tyrosine kinase in patients with solitary fibrous tumors.PTK6 regulates IGF-1-induced anchorage-independent survival.Insulin-sensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression.Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells.Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer.Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.Risk of breast cancer recurrence associated with carbohydrate intake and tissue expression of IGFI receptorPositive expression of insulin-like growth factor-1 receptor is associated with a positive hormone receptor status and a favorable prognosis in breast cancerInhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approachHyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer.GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines.Diabetes and cancer II: role of diabetes medications and influence of shared risk factors.Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancyDefining the pathway to insulin-like growth factor system targeting in cancer.Detection of estrogen-independent growth-stimulating activity in breast cancer tissues: implication for tumor aggressivenessMolecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability.ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis.Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetesMetformin and other biguanides in oncology: advancing the research agenda.Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial.Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk.Association between insulin-like growth factor-1 receptor (IGF1R) negativity and poor prognosis in a cohort of women with primary breast cancer.Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1)
P2860
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P2860
Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Phosphorylated insulin-like gr ...... d is related to poor survival.
@en
Phosphorylated insulin-like gr ...... d is related to poor survival.
@nl
type
label
Phosphorylated insulin-like gr ...... d is related to poor survival.
@en
Phosphorylated insulin-like gr ...... d is related to poor survival.
@nl
prefLabel
Phosphorylated insulin-like gr ...... d is related to poor survival.
@en
Phosphorylated insulin-like gr ...... d is related to poor survival.
@nl
P2093
P1433
P1476
Phosphorylated insulin-like gr ...... nd is related to poor survival
@en
P2093
Anna L Stratford
Eugene Park
Golareh Habibi
Hamid Masoudi
Helen E Jones
Jennifer H Law
Joan Carboni
Marco Gottardis
Michael Pollak
P304
10238-10246
P356
10.1158/0008-5472.CAN-08-2755
P407
P50
P577
2008-12-01T00:00:00Z