Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas.
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PARP expression in germ cell tumoursMolecular modeling and docking of small molecule inhibitors against NEK2Comparative expression profiling of testis-enriched genes regulated during the development of spermatogonial cells.Prognostic value of intratumoral carbonic anhydrase IX expression in testicular germ cell tumors.Increased Nek1 expression in renal cell carcinoma cells is associated with decreased sensitivity to DNA-damaging treatmentRole of NEK2A in human cancer and its therapeutic potentials.Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer.Fibrillin-1 (FBN-1) a new marker of germ cell neoplasia in situ.Clinical significance and prognostic value of Nek2 protein expression in colon cancer.Prognostic value of programmed-death-1 receptor (PD-1) and its ligand 1 (PD-L1) in testicular germ cell tumors.Targeting NEK2 as a promising therapeutic approach for cancer treatment.Local depletion of DNA methylation identifies a repressive p53 regulatory region in the NEK2 promoter.Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway.The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.Effect of NIMA-related kinase 2B on the sensitivity of breast cancer to paclitaxel in vitro and vivo.An Overview on Predictive Biomarkers of Testicular Germ Cell Tumors.High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness.Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism.Irreversible Nek2 kinase inhibitors with cellular activity.Identification by high-throughput screening of viridin analogs as biochemical and cell-based inhibitors of the cell cycle-regulated nek2 kinase.Molecular contribution to cleft palate production in cleft lip mice.New perspective on molecular markers as promising therapeutic targets in germ cell tumors.Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival.Expression profiling of 519 kinase genes in matched malignant peripheral nerve sheath tumor/plexiform neurofibroma samples is discriminatory and identifies mitotic regulators BUB1B, PBK and NEK2 as overexpressed with transformation.An up-date on epigenetic and molecular markers in testicular germ cell tumors.Importance of protein flexibility on molecular recognition: modeling binding mechanisms of aminopyrazine inhibitors to Nek2.NEK2 promotes hepatocellular carcinoma migration and invasion through modulation of the epithelial-mesenchymal transition.
P2860
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P2860
Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Increased expression and nucle ...... in human testicular seminomas.
@en
Increased expression and nucle ...... in human testicular seminomas.
@nl
type
label
Increased expression and nucle ...... in human testicular seminomas.
@en
Increased expression and nucle ...... in human testicular seminomas.
@nl
prefLabel
Increased expression and nucle ...... in human testicular seminomas.
@en
Increased expression and nucle ...... in human testicular seminomas.
@nl
P50
P356
P1476
Increased expression and nucle ...... in human testicular seminomas.
@en
P2093
Andrew M Fry
P304
P356
10.1002/PATH.2471
P50
P577
2009-02-01T00:00:00Z