Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
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Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5A shared interface mediates paramyxovirus interference with antiviral RNA helicases MDA5 and LGP2The measles virus V protein binds to p65 (RelA) to suppress NF-kappaB activityParamyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon inductionTLR3-dependent upregulation of RIG-I leads to enhanced cytokine production from cells infected with the parainfluenza virus SV5MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNAParamyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signalingThe Immune Response in Measles: Virus Control, Clearance and Protective ImmunityRIG-I in RNA virus recognitionInterferons and viruses: an evolutionary arms race of molecular interactionsViral evasion of intracellular DNA and RNA sensingNegative regulation of interferon-β gene expression during acute and persistent virus infectionsInduction of type I interferon by RNA viruses: cellular receptors and their substratesHuman parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates.Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.Measles virus-induced suppression of immune responses.Dissociation of paramyxovirus interferon evasion activities: universal and virus-specific requirements for conserved V protein amino acids in MDA5 interference.Interplay between innate immunity and negative-strand RNA viruses: towards a rational modelDistinct and overlapping roles of Nipah virus P gene products in modulating the human endothelial cell antiviral response.The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells.LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNATargeting viral dsRNA for antiviral prophylaxis.Identification of human parainfluenza virus type 2 (HPIV-2) V protein amino acid residues that reduce binding of V to MDA5 and attenuate HPIV-2 replication in nonhuman primatesFunctions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity.Antagonism of innate immunity by paramyxovirus accessory proteins.Henipaviruses employ a multifaceted approach to evade the antiviral interferon response.Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses.Measles virus, immune control, and persistence.A correlation of measles specific antibodies and the number of plasmacytoid dendritic cells is observed after measles vaccination in 9 month old infants.Inhibition of interferon regulatory factor 3 activation by paramyxovirus V protein.Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets.Control of the induction of type I interferon by Peste des petits ruminants virus.Type I interferons: diversity of sources, production pathways and effects on immune responses.Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 PhosphorylationDeep sequencing analysis of defective genomes of parainfluenza virus 5 and their role in interferon inductionDecreased SARI expression predicts poor prognosis of Chinese patients with non-small cell lung cancer.Similarities and differences in antagonism of neuron alpha/beta interferon responses by Venezuelan equine encephalitis and Sindbis alphaviruses.Differential cellular immune responses to wild-type and attenuated edmonston tag measles virus strains are primarily defined by the viral phosphoprotein gene.The regulation of type I interferon production by paramyxoviruses.Paramyxovirus activation and inhibition of innate immune responses.
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Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
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name
Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
@en
Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
@nl
type
label
Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
@en
Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
@nl
prefLabel
Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
@en
Mechanism of mda-5 Inhibition by paramyxovirus V proteins.
@nl
P2860
P356
P1433
P1476
Mechanism of mda-5 Inhibition by paramyxovirus V proteins
@en
P2093
J Andrejeva
K S Childs
P2860
P304
P356
10.1128/JVI.01768-08
P407
P577
2008-11-19T00:00:00Z