VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.
about
VE-PTP controls blood vessel development by balancing Tie-2 activityIntercellular adhesion molecules (ICAMs) and spermatogenesisStabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeabilityEndothelial Barrier and Its Abnormalities in Cardiovascular DiseaseRegulation of Endothelial Adherens Junctions by Tyrosine PhosphorylationOn, around, and through: neutrophil-endothelial interactions in innate immunityMechanisms regulating endothelial permeabilityAngiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling.Ve-ptp modulates vascular integrity by promoting adherens junction maturationAngiopoietin-Tie signalling in the cardiovascular and lymphatic systemsHow leukocytes trigger opening and sealing of gaps in the endothelial barrierThe regulation of transendothelial migration: new knowledge and new questionsDissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivoEndothelial CD47 promotes vascular endothelial-cadherin tyrosine phosphorylation and participates in T cell recruitment at sites of inflammation in vivoCortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivoUropod elongation is a common final step in leukocyte extravasation through inflamed vessels.VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formationRecurrent PTPRB and PLCG1 mutations in angiosarcoma.Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculatureEndothelial permeability and VE-cadherin: a wacky comradeship.Role of protein tyrosine phosphatase SHP2 in barrier function of pulmonary endothelium.Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency.Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculatureCellular players of hematopoietic stem cell mobilization in the bone marrow niche.Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca2+ entry regulates disassembly of adherens junctions.Innovations in studying in vivo cell behavior and pharmacology in complex tissues--microvascular endothelial cells in the spotlight.A potential role for angiopoietin 2 in the regulation of the blood-retinal barrier in diabetic retinopathyS1PR1 Tyr143 phosphorylation downregulates endothelial cell surface S1PR1 expression and responsiveness.γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylationInterfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo.Getting leukocytes to the site of inflammationMechanisms of leukocyte transendothelial migration.Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progressionMechanisms of transendothelial migration of leukocytes.The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species.Regulation of vascular integrity.Opening the flood-gates: how neutrophil-endothelial interactions regulate permeability.
P2860
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P2860
VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
VE-PTP maintains the endotheli ...... rin by leukocytes and by VEGF.
@en
VE-PTP maintains the endotheli ...... rin by leukocytes and by VEGF.
@nl
type
label
VE-PTP maintains the endotheli ...... rin by leukocytes and by VEGF.
@en
VE-PTP maintains the endotheli ...... rin by leukocytes and by VEGF.
@nl
prefLabel
VE-PTP maintains the endotheli ...... rin by leukocytes and by VEGF.
@en
VE-PTP maintains the endotheli ...... rin by leukocytes and by VEGF.
@nl
P2093
P2860
P50
P356
P1476
VE-PTP maintains the endotheli ...... rin by leukocytes and by VEGF.
@en
P2093
Alexander C Gamp
Astrid F Nottebaum
Christian Polaschegg
Giuseppe Cagna
Kristina Filippova
Maria Gabriele Bixel
Mark Winderlich
Olena Kamenyeva
Ruth Linnepe
Stefan Butz
P2860
P304
P356
10.1084/JEM.20080406
P407
P577
2008-11-17T00:00:00Z