Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway.
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Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cellsAutophagy of mitochondria: a promising therapeutic target for neurodegenerative disease.Crotoxin induces apoptosis and autophagy in human lung carcinoma cells in vitro via activation of the p38MAPK signaling pathwayIsolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cellsAutophagy: In the cROSshairs of cancer.Low molecular weight fucoidan against renal ischemia-reperfusion injury via inhibition of the MAPK signaling pathway.Tumor-targeting novel manganese complex induces ROS-mediated apoptotic and autophagic cancer cell death.miR-17-5p downregulation contributes to paclitaxel resistance of lung cancer cells through altering beclin1 expressionc-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cellsComputational prediction and experimental validation of a novel synthesized pan-PIM inhibitor PI003 and its apoptosis-inducing mechanisms in cervical cancer.Polyphyllin VII Induces an Autophagic Cell Death by Activation of the JNK Pathway and Inhibition of PI3K/AKT/mTOR Pathway in HepG2 Cells.High mannose-binding Pseudomonas fluorescens lectin (PFL) downregulates cell surface integrin/EGFR and induces autophagy in gastric cancer cellsThe presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolismApoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells.B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy.Autophagic pathways as new targets for cancer drug development.EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells.Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.Targeting autophagic pathways for cancer drug discoverySynergistic effect of sunlight induced photothermal conversion and H2O2 release based on hybridized tungsten oxide gel for cancer inhibition.The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy.Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents.Anti-tumor and anti-viral activities of Galanthus nivalis agglutinin (GNA)-related lectins.Musca domestica larva lectin induces apoptosis in BEL-7402 cells through a Ca(2+)/JNK-mediated mitochondrial pathway.Could plant lectins become promising anti-tumour drugs for causing autophagic cell death?Regulation of autophagy by kinases.Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy.Lectins with anti-HIV activity: a review.Identification of microRNA-regulated autophagic pathways in plant lectin-induced cancer cell death.Lectins with potential for anti-cancer therapy.Phytoconstituents as apoptosis inducing agents: strategy to combat cancerChemopreventive role of food-derived proteins and peptides: A review.Procyanidins from Vitis vinifera seeds induce apoptotic and autophagic cell death via generation of reactive oxygen species in squamous cell carcinoma cells.Modulation of Autophagy by a Thioxanthone Decreases the Viability of Melanoma Cells.Role of reactive oxygen species-mediated MAPK and NF-κB activation in polygonatum cyrtonema lectin-induced apoptosis and autophagy in human lung adenocarcinoma A549 cells.Unravelling the relationship between macroautophagy and mitochondrial ROS in cancer therapy.Redox regulation of autophagy in skeletal muscle.Molecular Functions of Glycoconjugates in Autophagy.A novel manganese complex LMnAc selectively kills cancer cells by induction of ROS-triggered and mitochondrial-mediated cell death.A synthetic curcumin derivative hydrazinobenzoylcurcumin induces autophagy in A549 lung cancer cells.
P2860
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P2860
Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Polygonatum cyrtonema lectin i ...... -mediated ROS-p38-p53 pathway.
@en
Polygonatum cyrtonema lectin i ...... -mediated ROS-p38-p53 pathway.
@nl
type
label
Polygonatum cyrtonema lectin i ...... -mediated ROS-p38-p53 pathway.
@en
Polygonatum cyrtonema lectin i ...... -mediated ROS-p38-p53 pathway.
@nl
prefLabel
Polygonatum cyrtonema lectin i ...... -mediated ROS-p38-p53 pathway.
@en
Polygonatum cyrtonema lectin i ...... -mediated ROS-p38-p53 pathway.
@nl
P2093
P921
P1433
P1476
Polygonatum cyrtonema lectin i ...... -mediated ROS-p38-p53 pathway.
@en
P2093
P356
10.1016/J.CANLET.2008.09.042
P407
P577
2008-11-17T00:00:00Z