Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. - Wikidata - awgldk - TriplyDB

Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.

Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.

http://www.wikidata.org/entity/Q39917756

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The Role of Endoplasmic Reticulum Stress and Unfolded Protein Response in Atherosclerosis Endoplasmic Reticulum Stress in the Diabetic Kidney, the Good, the Bad and the Ugly Endoplasmic reticulum stress and type 2 diabetes 6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α Phenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cells The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha Endoplasmic Reticulum Stress and Homeostasis in Reproductive Physiology and Pathology.Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas.Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery.Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2alpha in caspase-3/7-deficient cells.Activation of senescence and aging characteristics by mitochondrially generated ROS: how are they linked?A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway Identification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death.Signaling cell death from the endoplasmic reticulum stress response The endoplasmic reticulum stress response and diabetic kidney disease.Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts.Adiponectin protects rat myocardium against chronic intermittent hypoxia-induced injury via inhibition of endoplasmic reticulum stress.Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes.Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1.Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction.STIMs and Orai1 regulate cytokine production in spinal astrocytes.Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses.4‑Phenylbutyrate protects rat skin flaps against ischemia‑reperfusion injury and apoptosis by inhibiting endoplasmic reticulum stress.RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway.Laxative effects of Liriope platyphylla are tightly correlated with suppression of endoplasmic reticulum stress in loperamide-induced constipation of SD rats.Integration of apoptosis signal-regulating kinase 1-mediated stress signaling with the Akt/protein kinase B-IκB kinase cascade.Mechanisms of radiation toxicity in transformed and non-transformed cells Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress IMB-6G, a novel N-substituted sophoridinic acid derivative, induces endoplasmic reticulum stress-mediated apoptosis via activation of IRE1α and PERK signaling.Endoplasmic reticulum stress: its role in disease and novel prospects for therapy.Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences.Targeting ASK1 in ER stress-related neurodegenerative diseases.Adaptive and Pathogenic Responses to Stress by Stem Cells during Development.Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress.Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome.Targeting endoplasmic reticulum stress in metabolic disease.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins.Non-Hodgkin's B-cell lymphoma: advances in molecular strategies targeting drug resistance.Targeting the unfolded protein response in disease.

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P2860

Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.

http://www.wikidata.org/entity/Q39917756

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2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Chemical biology investigation ...... protective modulators of ASK1.

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Chemical biology investigation ...... protective modulators of ASK1.

@nl

type

label

Chemical biology investigation ...... protective modulators of ASK1.

@en

Chemical biology investigation ...... protective modulators of ASK1.

@nl

prefLabel

Chemical biology investigation ...... protective modulators of ASK1.

@en

Chemical biology investigation ...... protective modulators of ASK1.

@nl

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Journal of Biological Chemistry

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Chemical biology investigation ...... protective modulators of ASK1.

@en

P2093

Chih-Wen Shu

http://www.w3.org/2001/XMLSchema#string

Chung-Wai Shiau

http://www.w3.org/2001/XMLSchema#string

Daniel Grant

http://www.w3.org/2001/XMLSchema#string

InKi Kim

http://www.w3.org/2001/XMLSchema#string

John C Reed

http://www.w3.org/2001/XMLSchema#string

Nicholas D P Cosford

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Stefan Vasile

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Wenjie Xu

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P2860

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

Endoplasmic reticulum stress: cell life and death decisions.

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins

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1593-1603

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10.1074/JBC.M807308200

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3

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284

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2008-11-12T00:00:00Z

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19004820

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endoplasmic reticulum

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2615512

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