Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells. - Wikidata - awgldk - TriplyDB

Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.

Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.

http://www.wikidata.org/entity/Q39929967

about

Pregnancy-specific glycoprotein 1 induces endothelial tubulogenesis through interaction with cell surface proteoglycans Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting Syndecan-4 signaling at a glance Structural Basis for the Association of the Redox-sensitive Target of Rapamycin FATC Domain with Membrane-mimetic Micelles Where is mTOR and what is it doing there?The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease.The mTOR-FAK mechanotransduction signaling axis for focal adhesion maturation and cell proliferation.Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-alpha-dependent Akt activation in endosomes Heparan sulfate proteoglycans.Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes.Syndecan-1 regulates vascular smooth muscle cell phenotype.The role of the Niemann-Pick disease, type C1 protein in adipocyte insulin action.Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.A shift of the TOR adaptor from Rictor towards Raptor by semaphorin in C. elegans.Rapid mitogenic regulation of the mTORC1 inhibitor, DEPTOR, by phosphatidic acid.Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons mTOR complex 2 signaling and functions Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1 HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells The syndecan-4/protein kinase Cα pathway mediates prostaglandin E2-induced extracellular regulated kinase (ERK) activation in endothelial cells and angiogenesis in vivo.Syndecan-4 modulates the proliferation of neural cells and the formation of CaP axons during zebrafish embryonic neurogenesis.Auxiliary and autonomous proteoglycan signaling networks Syndecan 4 signaling is required for exercise-induced cardiac hypertrophy.Syndecan 4 regulates FGFR1 signaling in endothelial cells by directing macropinocytosis Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling.Phospholipase D1 deficiency in mice causes nonalcoholic fatty liver disease via an autophagy defect.Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway.Ceramide and ceramide 1-phosphate in health and disease.mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.Mammalian TOR signaling to the AGC kinases.Development and Growth of the Avian Pectoralis Major (Breast) Muscle: Function of Syndecan-4 and Glypican-1 in Adult Myoblast Proliferation and Differentiation.Heparan Sulfate Proteoglycan Deficiency Up-Regulates the Intracellular Production of Nitric Oxide in Chinese Hamster Ovary Cell Lines.Killing two birds with one stone: dual blockade of integrin and FGF signaling through targeting syndecan-4 in postoperative capsular opacification.Gonadotropin releasing hormone activation of the mTORC2/Rictor complex regulates actin remodeling and ERK activity in LβT2 cells.Characterization of residue-dependent differences in the peripheral membrane association of the FATC domain of the kinase 'target of rapamycin' by NMR and CD spectroscopy.PI3K/Akt responses to oxytocin stimulation in Caco2BB gut cells.Syndecan-4 is a major syndecan in primary human endothelial cells in vitro, modulated by inflammatory stimuli and involved in wound healing

P2860

Q24614349-7472EB7E-12C1-4835-B95D-3701A9960A1F Q26783004-D78C81EA-4EE3-4199-A20C-CCA05D8E8435 Q26865478-6C819F05-2980-406D-A828-6EB679D88E82 Q27658819-EBDEF61C-0423-4254-BBF6-57F4A4894557 Q28305068-7D3E2AF2-6212-4EC5-8B6C-903E2FF946E4 Q30235555-0F0DBF31-5C3C-4B3D-B1EB-DDB68A4E277C Q30275585-54BA4661-5BFC-45DD-B3F0-D8095F2BE888 Q30357240-B2B02B75-3535-42A9-8ADE-AA892F36FBC2 Q30437384-81961FFB-D3B3-44BA-A6A0-3B63C28DB0C9 Q34509498-488561CB-56F8-412D-B473-BD9AE152EB3F Q35059448-258E404D-91B6-4AFC-996E-A1DC023E733F Q35063172-E6FCF567-9938-4F22-926E-1377C89CBD88 Q35108169-A397AD92-D2D4-4083-82C4-12704637E978 Q35154081-B8A5C607-D5AF-4FA1-B44A-5898D009F73B Q35176340-EB196607-E72A-40D4-B6DC-698C16F2A907 Q35367042-8E3AE5AD-59EC-47A2-999B-EDA7564DC92C Q35593768-33F93FC7-D58E-4E57-B2E8-ACA7F52E5342 Q35634446-FF80E8C2-D5FC-411C-B464-1A0516BBEBAC Q35878519-17D854B6-09E5-4381-9DDB-7B319C49AA83 Q36245893-EF6143A6-88D0-4F5E-8C8B-2193D8663280 Q36312784-D05F3118-24EE-4B66-9CB1-A5619A45DA56 Q36812395-094C916B-789E-4010-B345-84A458E6D70D Q36864680-F64AB37A-1CCD-45A3-B9B3-21949393BD71 Q37090575-271FF2C3-BD32-4664-B1E4-93F3095661CA Q37216988-DD39EDCE-1590-427D-BDBF-37E06A865F9F Q37308214-A1124600-2734-4033-86A6-3E835331FAB9 Q37428684-5948BB26-A86D-4599-839B-ADD89FB5FC93 Q37436623-2AC562A1-F59B-4A2A-91A2-7FD05F6EAC92 Q37504529-CC571FE1-4773-4272-BF09-D4FA77495983 Q37638030-3F2610CE-7741-405C-BEA8-576A1C73AF06 Q37688315-1911AF55-629B-4922-BBFB-1331E1E7BDD0 Q37929699-112CAB2A-0372-4D25-A25B-A9572DC30E06 Q37943416-B6FD7AE4-8547-40EF-A09E-686332D08E2D Q38402862-1C388106-368D-40DD-B717-785B0F0EC24D Q38612342-EF90E82C-7DA9-4234-999E-C83BAB78C12B Q38658250-6020741F-7108-42A2-B25C-5D21F378B54D Q38744094-79ACAC36-3A0F-4399-A2B0-470AE69CD70E Q39215313-EF9297FA-5AD4-42AC-A182-6C59DA6335F6 Q39512084-81207069-650B-4FF6-9A32-6B6A497DA3FC Q41599683-B7128939-B3E9-4641-8917-2FBA3F632ABF

P2860

Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.

http://www.wikidata.org/entity/Q39929967

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Syndecan-4 regulates subcellul ...... t manner in endothelial cells.

@en

Syndecan-4 regulates subcellul ...... t manner in endothelial cells.

@nl

type

label

Syndecan-4 regulates subcellul ...... t manner in endothelial cells.

@en

Syndecan-4 regulates subcellul ...... t manner in endothelial cells.

@nl

prefLabel

Syndecan-4 regulates subcellul ...... t manner in endothelial cells.

@en

Syndecan-4 regulates subcellul ...... t manner in endothelial cells.

@nl

P1433

Q39929967-14392F2C-D57B-4F02-8DAE-D22E7D9C68C9

P1476

Q39929967-4DDB05D0-B3BA-4F5B-A5C6-B841DAEF073B

P2093

Q39929967-3CE8B479-DE72-4099-9E42-F8A26886F226

Q39929967-70690557-8E22-4031-A9CD-4F6133776CDA

Q39929967-875DE173-605C-4647-BD88-47F282137B55

Q39929967-F75A2FBC-F6B5-42CF-8A02-79D6F7201CD7

P2860

Q39929967-00179838-81D8-448A-9826-B75F417083A5

Q39929967-0528DB08-C519-43B1-9ABC-B5DA0E2F6EAA

Q39929967-0B4317F4-71CE-4ABE-AA66-2B352FFF4E9C

Q39929967-16CD503F-9C13-46F7-AC7F-E1C4FD25714F

Q39929967-1F2DC2BA-BB6A-4215-BF6B-168B2BD65907

Q39929967-26CF7FB4-0850-4433-8FA2-5044D9836476

Q39929967-329197A9-CDC8-4D26-B51C-31013533359A

Q39929967-4F21440E-90C1-48B5-90FD-245EB1256196

Q39929967-56F5A969-6B08-494F-99CA-5227AA749091

Q39929967-5925488D-CF96-4052-B9DE-91D4609A8550

P304

Q39929967-49F2DE53-D304-476E-8C13-7EF515A4DD44

P31

Q39929967-9F52AF9B-061B-4408-9E7F-D8DE75D077EC

P356

Q39929967-21057809-A211-4F40-9C13-1EBF171971C9

P433

Q39929967-5A45D3A9-3F30-4B83-9891-24AC7EC9D542

P478

Q39929967-7072B108-B896-428D-9570-8908A361D2DD

P50

Q39929967-F6032E15-01D8-4CF4-9104-63480B1B6954

P577

Q39929967-E2ECE986-7B15-4B09-AEE1-3607B7F952BD

P5875

Q39929967-8C2223EA-E7EA-48E6-8229-DE139D076F51

P698

Q39929967-1A65F99A-4FC3-4697-85EE-A5F8DAE1C9A8

P921

Q39929967-DB8659B1-BD04-433A-A9CE-4177879BC4E6

P932

Q39929967-560FF644-74D6-4F45-963D-FA81C8A64CA3

P356

J.MOLCEL.2008.09.010

P1433

P1476

Syndecan-4 regulates subcellul ...... t manner in endothelial cells.

@en

P2093

Chohreh Partovian

http://www.w3.org/2001/XMLSchema#string

Kathleen A Martin

http://www.w3.org/2001/XMLSchema#string

Rong Ju

http://www.w3.org/2001/XMLSchema#string

Zhen W Zhuang

http://www.w3.org/2001/XMLSchema#string

P2860

Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

Akt1 in endothelial cell and angiogenesis

Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

Clustering induces redistribution of syndecan-4 core protein into raft membrane domains

Control of morphology, cytoskeleton and migration by syndecan-4

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

P304

140-149

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.MOLCEL.2008.09.010

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

32

http://www.w3.org/2001/XMLSchema#string

P50

P577

2008-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23314447

http://www.w3.org/2001/XMLSchema#string

P698

18851840

http://www.w3.org/2001/XMLSchema#string

P921

P932

2578831

http://www.w3.org/2001/XMLSchema#string