Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling.
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Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells.FJU-C4, a new 2-pyridone compound, attenuates lipopolysaccharide-induced systemic inflammation via p38MAPK and NF-κB in miceThe topical application of low-temperature argon plasma enhances the anti-inflammatory effect of Jaun-ointment on DNCB-induced NC/Nga mice.Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus.Is nitric oxide decrease observed with naphthoquinones in LPS stimulated RAW 264.7 macrophages a beneficial property?Cbl-b-regulated extracellular signal-regulated kinase signaling is involved in the shikonin-induced apoptosis of lung cancer cells in vitro.Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1.Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis.Gelam honey scavenges peroxynitrite during the immune responseInhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells.Shikonin changes the lipopolysaccharide-induced expression of inflammation-related genes in macrophages.Salidroside attenuates LPS-stimulated activation of THP-1 cell-derived macrophages through down-regulation of MAPK/NF-kB signaling pathways.Cryptotanshinone suppressed inflammatory cytokines secretion in RAW264.7 macrophages through inhibition of the NF-κB and MAPK signaling pathways.Shikonin Suppresses Human T Lymphocyte Activation through Inhibition of IKK β Activity and JNK PhosphorylationEvaluation of radical scavenging properties of shikonin.Therapeutic effect of a hydroxynaphthoquinone fraction on dextran sulfate sodium-induced ulcerative colitis.Aspirin suppresses TNF-α-induced MMP-9 expression via NF-κB and MAPK signaling pathways in RAW264.7 cells.Shikonin protects against D-Galactosamine and lipopolysaccharide-induced acute hepatic injury by inhibiting TLR4 signaling pathway.Anti-inflammatory and analgesic activity of Alkanna bracteosa and Alkanna tricophila.
P2860
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P2860
Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Shikonin derivatives inhibited ...... n of MAPK/NF-kappaB signaling.
@en
Shikonin derivatives inhibited ...... n of MAPK/NF-kappaB signaling.
@nl
type
label
Shikonin derivatives inhibited ...... n of MAPK/NF-kappaB signaling.
@en
Shikonin derivatives inhibited ...... n of MAPK/NF-kappaB signaling.
@nl
prefLabel
Shikonin derivatives inhibited ...... n of MAPK/NF-kappaB signaling.
@en
Shikonin derivatives inhibited ...... n of MAPK/NF-kappaB signaling.
@nl
P2093
P1476
Shikonin derivatives inhibited ...... on of MAPK/NF-kappaB signaling
@en
P2093
Cheng Hui Lin
Chien Ming Hu
Ching Yi Chang
Kou Lung Lin
Yu Wen Cheng
P304
P356
10.1016/J.JEP.2008.09.002
P50
P577
2008-09-12T00:00:00Z