Interdomain hybrid Tet proteins confer tetracycline resistance only when they are derived from closely related members of the tet gene family
about
Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistanceMosaic tetracycline resistance genes encoding ribosomal protection proteinsThe lactose transport protein is a cooperative dimer with two sugar translocation pathwaysFe(2+)-tetracycline-mediated cleavage of the Tn10 tetracycline efflux protein TetA reveals a substrate binding site near glutamine 225 in transmembrane helix 7.Active efflux, a common mechanism for biocide and antibiotic resistance.Isolation of tetracycline-resistant Megasphaera elsdenii strains with novel mosaic gene combinations of tet(O) and tet(W) from swineProperties of permease dimer, a fusion protein containing two lactose permease molecules from Escherichia coli.Sequencing and expression of a gene encoding a bile acid transporter from Eubacterium sp. strain VPI 12708.Active efflux mechanisms for antimicrobial resistance.Tet protein domains interact productively to mediate tetracycline resistance when present on separate polypeptidesGenetic analysis suggests functional interactions between the N- and C-terminal domains of the TetA(C) efflux pump encoded by pBR322.Genetic analysis of the tetA(C) gene on plasmid pBR322.TetL tetracycline efflux protein from Bacillus subtilis is a dimer in the membrane and in detergent solution.Second-site suppressor mutations for the serine 202 to phenylalanine substitution within the interdomain loop of the tetracycline efflux protein Tet(C).The NH2-terminal half of the Tn10-specified tetracycline efflux protein TetA contains a dimerization domain.The in vivo assembly and function of the N- and C-terminal halves of the Tn10-encoded TetA protein in Escherichia coli.
P2860
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P2860
Interdomain hybrid Tet proteins confer tetracycline resistance only when they are derived from closely related members of the tet gene family
description
1990 nî lūn-bûn
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1990年の論文
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1990年学术文章
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1990年学术文章
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1990年学术文章
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name
Interdomain hybrid Tet protein ...... members of the tet gene family
@en
Interdomain hybrid Tet protein ...... embers of the tet gene family.
@nl
type
label
Interdomain hybrid Tet protein ...... members of the tet gene family
@en
Interdomain hybrid Tet protein ...... embers of the tet gene family.
@nl
prefLabel
Interdomain hybrid Tet protein ...... members of the tet gene family
@en
Interdomain hybrid Tet protein ...... embers of the tet gene family.
@nl
P2860
P1476
Interdomain hybrid Tet protein ...... members of the tet gene family
@en
P2093
P2860
P304
P356
10.1128/JB.172.5.2303-2312.1990
P577
1990-05-01T00:00:00Z