Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells.
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Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell FunctionWhen stem cells grow old: phenotypes and mechanisms of stem cell agingEpigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical ImplicationsAutophagy in stem cells.Genetic regulation of thymocyte progenitor agingHematopoietic stem cell niche maintenance during homeostasis and regenerationAge-dependent dysregulation of innate immunityEpigenetic regulation of hematopoietic stem cell agingStem cell heterogeneity: implications for aging and regenerative medicineSelf-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansionHematopoietic Stem Cells in Regenerative Medicine: Astray or on the Path?Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow MicroenvironmentImmunosenescence in renal transplantation: a changing balance of innate and adaptive immunityImpact of genomic damage and ageing on stem cell functionStochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemiaAging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitorsAccumulation of DNA damage in the aged hematopoietic stem cell compartmentSingle cell transcriptomics reveals unanticipated features of early hematopoietic precursorsCdc42 and aging of hematopoietic stem cells.Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.Loss of P2Y₁₄ results in an arresting response to hematological stressQuiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycleEpigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem CellsAging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cellsClearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in miceLatexin is down-regulated in hematopoietic malignancies and restoration of expression inhibits lymphoma growth.Concise review: hematopoietic stem cell aging and the prospects for rejuvenationClonal-level responses of functionally distinct hematopoietic stem cells to trophic factors.Enhanced hematopoietic stem cell function mediates immune regeneration following sex steroid blockade.Measuring the aging process in stem cellsImmune aging, dysmetabolism, and inflammation in neurological diseases.Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation.A Detailed Characterization of the Dysfunctional Immunity and Abnormal Myelopoiesis Induced by Severe Shock and Trauma in the Aged.Index sorting resolves heterogeneous murine hematopoietic stem cell populationsHuman and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells.Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate.Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells.Hematopoietic lineage skewing and intestinal epithelia degeneration in aged mice with telomerase RNA component deletion.HSC Aging and Senescent Immune Remodeling.
P2860
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P2860
Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Clonal analysis reveals multip ...... rine hematopoietic stem cells.
@en
Clonal analysis reveals multip ...... rine hematopoietic stem cells.
@nl
type
label
Clonal analysis reveals multip ...... rine hematopoietic stem cells.
@en
Clonal analysis reveals multip ...... rine hematopoietic stem cells.
@nl
prefLabel
Clonal analysis reveals multip ...... rine hematopoietic stem cells.
@en
Clonal analysis reveals multip ...... rine hematopoietic stem cells.
@nl
P2093
P2860
P356
P1476
Clonal analysis reveals multip ...... rine hematopoietic stem cells.
@en
P2093
Brad Dykstra
Gerald de Haan
Jaring Schreuder
Martha Ritsema
Sandra Olthof
P2860
P304
P356
10.1084/JEM.20111490
P407
P577
2011-11-21T00:00:00Z