Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs. - Wikidata - awgldk - TriplyDB

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

http://www.wikidata.org/entity/Q39956127

about

Enzastaurin has anti-tumour effects in lung cancers with overexpressed JAK pathway molecules.Molecular interaction of a kinase inhibitor midostaurin with anticancer drug targets, S100A8 and EGFR: transcriptional profiling and molecular docking study for kidney cancer therapeutics Phase 1 study of combination treatment with PTK 787/ZK 222584 and cetuximab for patients with advanced solid tumors: safety, pharmacokinetics, pharmacodynamics analysis.Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.Beyond KRAS: perspectives on new potential markers of intrinsic and acquired resistance to epidermal growth factor receptor inhibitors in metastatic colorectal cancer A phase I dose-escalation and pharmacokinetic study of enzastaurin and erlotinib in patients with advanced solid tumors MET/PKCbeta expression correlate with metastasis and inhibition is synergistic in lung cancer.Potential of casein kinase I in digestive cancer screening.Protein kinase C and cancer: what we know and what we do not.Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cells

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Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

http://www.wikidata.org/entity/Q39956127

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

@en

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

@nl

type

label

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

@en

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

@nl

prefLabel

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

@en

Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

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British Journal of Cancer

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Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.

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P2093

F Ciardiello

http://www.w3.org/2001/XMLSchema#string

M Lahn

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R Bianco

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R Caputo

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S Pepe

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T Gelardi

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V Damiano

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P2860

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

EGFR antagonists in cancer treatment

ERBB receptors and cancer: the complexity of targeted inhibitors

PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways.

Phase I pharmacokinetic and pharmacodynamic study of the oral protein kinase C beta-inhibitor enzastaurin in combination with gemcitabine and cisplatin in patients with advanced cancer.

Clinical translation of angiogenesis inhibitors.

Protein kinase C isozymes as potential targets for anticancer therapy.

Resistance to epidermal growth factor receptor-targeted therapy.

Epidermal growth factor receptor targeting in cancer.

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473-480

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scholarly article

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10.1038/SJ.BJC.6604493

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3

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99

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Gennaro Daniele

Giampaolo Tortora

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23135743

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1023783898

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18665191

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2527788

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