Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma.
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Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyAberrant activation of the hedgehog signaling pathway in malignant hematological neoplasmsRapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.Targeting Hedgehog--a cancer stem cell pathwayFrequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic eraBMI1 polycomb group protein acts as a master switch for growth and death of tumor cells: regulates TCF4-transcriptional factor-induced BCL2 signaling.Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.Hedgehog pathway as a drug target: Smoothened inhibitors in development.Defining causative factors contributing in the activation of hedgehog signaling in diffuse large B-cell lymphoma.Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.Construction and application of a zebrafish array comparative genomic hybridization platformProfile of vismodegib and its potential in the treatment of advanced basal cell carcinomaLearning from Jekyll to control Hyde: Hedgehog signaling in development and cancer.The utility of hedgehog signaling pathway inhibition for cancer.New prospects for drug development: the hedgehog pathway revealed. Focus on hematologic malignancies.Nonclassical hedgehog-GLI signaling and its clinical implications.New insight into hedgehog signaling in hematological malignancies.Hedgehog signaling in cancer stem cells: a focus on hematological cancers.Novel targeted therapeutics for mantle cell lymphoma--what's on the horizon?Novel treatment for mantle cell lymphoma including therapy-resistant tumor by NF-κB and mTOR dual-targeting approach.Brief report: SRF-dependent MiR-210 silences the sonic hedgehog signaling during cardiopoesis.Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development.Novel therapy for therapy-resistant mantle cell lymphoma: multipronged approach with targeting of hedgehog signaling.Smoothened as a new therapeutic target for human osteosarcoma.Inhibition of p70S6K2 down-regulates Hedgehog/GLI pathway in non-small cell lung cancer cell linesHedgehog inhibitors selectively target cell migration and adhesion of mantle cell lymphoma in bone marrow microenvironment.Colon Cancer Stem Cells: Bench-to-Bedside-New Therapeutical Approaches in Clinical Oncology for Disease Breakdown.C-H-Functionalization logic guides the synthesis of a carbacyclopamine analog.Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling.Identification of novel target proteins in sebaceous gland carcinoma.Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells.Emodin Impairs Radioresistance of Human Osteosarcoma Cells by Suppressing Sonic Hedgehog Signaling.Lentivirus-mediated silencing of the PTC1 and PTC2 genes promotes recovery from spinal cord injury by activating the Hedgehog signaling pathway in a rat model.Gastroblastoma harbors a recurrent somatic MALAT1-GLI1 fusion gene.Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization.Global gene expression profiling and tissue microarray reveal novel candidate genes and down-regulation of the tumor suppressor gene CAV1 in sporadic vestibular schwannomas.Polo-Like Kinase 1: A Novel Target for the Treatment of Therapy-Resistant Mantle Cell Lymphoma
P2860
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P2860
Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Targeting of sonic hedgehog-GL ...... rapy for mantle cell lymphoma.
@en
Targeting of sonic hedgehog-GL ...... rapy for mantle cell lymphoma.
@nl
type
label
Targeting of sonic hedgehog-GL ...... rapy for mantle cell lymphoma.
@en
Targeting of sonic hedgehog-GL ...... rapy for mantle cell lymphoma.
@nl
prefLabel
Targeting of sonic hedgehog-GL ...... rapy for mantle cell lymphoma.
@en
Targeting of sonic hedgehog-GL ...... rapy for mantle cell lymphoma.
@nl
P2093
P1476
Targeting of sonic hedgehog-GL ...... rapy for mantle cell lymphoma.
@en
P2093
Avadhut D Joshi
Corey M Munger
Ganapati V Hegde
Katy Emanuel
Shantaram S Joshi
Timothy C Greiner
P304
P356
10.1158/1535-7163.MCT-07-2118
P577
2008-06-04T00:00:00Z