Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
about
Beyond desensitization: physiological relevance of arrestin-dependent signaling.Thromboxane and the thromboxane receptor in cardiovascular disease.The thromboxane synthase and receptor signaling pathway in cancer: an emerging paradigm in cancer progression and metastasis.Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein -1 (MCP-1)/chemokine (C-C motif) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells.Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer.18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer.Delineation of a conserved arrestin-biased signaling repertoire in vivo.Regulation of the tumor suppressor FOXO3 by the thromboxane-A2 receptors in urothelial cancerFulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation.Non-steroid anti-inflammatory drugs, prostaglandins, and cancer.Thromboxane A2 Receptor Inhibition Suppresses Multiple Myeloma Cell Proliferation by Inducing p38/c-Jun N-terminal Kinase (JNK) Mitogen-activated Protein Kinase (MAPK)-mediated G2/M Progression Delay and Cell Apoptosis.Therapeutic potential of β-arrestin- and G protein-biased agonists.β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivoRole for the thromboxane A2 receptor β-isoform in the pathogenesis of intrauterine growth restriction.Down-regulation of β-arrestin2 promotes tumour invasion and indicates poor prognosis of hepatocellular carcinomaInvolvement of β-arrestins in cancer progression.Prostanoids receptors signaling in different diseases/cancers progression.Protein kinase C-related kinase 1 and 2 play an essential role in thromboxane-mediated neoplastic responses in prostate cancer.Thromboxane A2 exerts promoting effects on cell proliferation through mediating cyclooxygenase-2 signal in lung adenocarcinoma cells.Urinary thromboxane B2 and thromboxane receptors in bladder cancer: opportunity for detection and monitoringTranslating in vitro ligand bias into in vivo efficacy.The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.The Internalization of Neurotensin by the Low-Affinity Neurotensin Receptors (NTSR2 and vNTSR2) Activates ERK 1/2 in Glioma Cells and Allows Neurotensin-Polyplex Transfection of tGAS1.Expression of the TPα and TPβ isoforms of the thromboxane prostanoid receptor (TP) in prostate cancer: clinical significance and diagnostic potential.Thromboxane A₂ receptor signaling facilitates tumor colonization through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells.
P2860
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P2860
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
@en
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
@nl
type
label
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
@en
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
@nl
prefLabel
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
@en
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
@nl
P2093
P1433
P1476
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis
@en
P2093
Anthony W Ashton
Dennis K Watson
Elizabeth Garrett-Mayer
Mohamed A Ghoneim
Omar Moussa
Perry V Halushka
P304
P356
10.1158/0008-5472.CAN-07-6560
P407
P577
2008-06-01T00:00:00Z