Alterations in RNA-binding activities of IRES-regulatory proteins as a mechanism for physiological variability and pathological dysregulation of IGF-IR translational control in human breast tumor cells.
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Functional interplay between RNA-binding protein HuR and microRNAsCurrent Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and TreatmentOverexpression of hnRNPC2 induces multinucleation by repression of Aurora B in hepatocellular carcinoma cellsIRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cellsMinireview: posttranscriptional regulation of the insulin and insulin-like growth factor systemsNorthwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor gamma-independent pathway.The human IGF1R IRES likely operates through a Shine-Dalgarno-like interaction with the G961 loop (E-site) of the 18S rRNA and is kinetically modulated by a naturally polymorphic polyU loop.DNA and RNA quadruplex-binding proteins.Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiationHuR function in disease.Deregulation of Internal Ribosome Entry Site-Mediated p53 Translation in Cancer Cells with Defective p53 Response to DNA Damage.Biomarkers and the genetics of early neoplastic lesions.Small molecule inhibitors of IRES-mediated translation.Mutant tristetraprolin: a potent inhibitor of malignant glioma cell growth.The insulin receptor cellular IRES confers resistance to eIF4A inhibition.MicroRNA-214 Reduces Insulin-like Growth Factor-1 (IGF-1) Receptor Expression and Downstream mTORC1 Signaling in Renal Carcinoma Cells.Posttranscriptional regulation of insulin family ligands and receptorsInsulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent.Factors interacting with HIF-1alpha mRNA: novel therapeutic targets.IGF-IR and its inhibitors in gastrointestinal carcinomas (Review).Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics.The human insulin receptor mRNA contains a functional internal ribosome entry segmentTranslational control of the undifferentiated phenotype in ER‑positive breast tumor cells: Cytoplasmic localization of ERα and impact of IRES inhibition.
P2860
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P2860
Alterations in RNA-binding activities of IRES-regulatory proteins as a mechanism for physiological variability and pathological dysregulation of IGF-IR translational control in human breast tumor cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Alterations in RNA-binding act ...... l in human breast tumor cells.
@en
Alterations in RNA-binding act ...... l in human breast tumor cells.
@nl
type
label
Alterations in RNA-binding act ...... l in human breast tumor cells.
@en
Alterations in RNA-binding act ...... l in human breast tumor cells.
@nl
prefLabel
Alterations in RNA-binding act ...... l in human breast tumor cells.
@en
Alterations in RNA-binding act ...... l in human breast tumor cells.
@nl
P2093
P356
P1476
Alterations in RNA-binding act ...... l in human breast tumor cells.
@en
P2093
Hyoungsoo Choi
Nateka L Jackson
Peter D Emanuel
Peter H King
Scott W Blume
Zheng Meng
P2860
P304
P356
10.1002/JCP.21486
P577
2008-10-01T00:00:00Z