Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation.
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Lanthipeptides: chemical synthesis versus in vivo biosynthesis as tools for pharmaceutical productionBacteriocins: Novel Solutions to Age Old Spore-Related Problems?Bioengineering Lantibiotics for Therapeutic SuccessType AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of actionLantibiotic resistance.Bioengineered nisin A derivatives with enhanced activity against both Gram positive and Gram negative pathogensA bioengineered nisin derivative to control biofilms of Staphylococcus pseudintermediusProspects of In vivo Incorporation of Non-canonical Amino Acids for the Chemical Diversification of Antimicrobial PeptidesDissecting structural and functional diversity of the lantibiotic mersacidinBacterial display and screening of posttranslationally thioether-stabilized peptides.Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.Investigating the importance of charged residues in lantibiotics.Saturation mutagenesis of lysine 12 leads to the identification of derivatives of nisin A with enhanced antimicrobial activity.The presence of modifiable residues in the core peptide part of precursor nisin is not crucial for precursor nisin interactions with NisB- and NisCMechanism of inhibition of Bacillus anthracis spore outgrowth by the lantibiotic nisin.Homologues and bioengineered derivatives of LtnJ vary in ability to form D-alanine in the lantibiotic lacticin 3147.Chemical synthesis and biological activity of analogues of the lantibiotic epilancin 15X.The Clostridium difficile cpr locus is regulated by a noncontiguous two-component system in response to type A and B lantibiotics.Inhibition of Bacillus anthracis spore outgrowth by nisinStudies with bioengineered Nisin peptides highlight the broad-spectrum potency of Nisin V.Therapeutic potential of type A (I) lantibiotics, a group of cationic peptide antibiotics.Investigation of the substrate specificity of lacticin 481 synthetase by using nonproteinogenic amino acids.Manipulation of charged residues within the two-peptide lantibiotic lacticin 3147.Ribosomally synthesized and post-translationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis.Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.Saturation mutagenesis of selected residues of the α-peptide of the lantibiotic lacticin 3147 yields a derivative with enhanced antimicrobial activityMode of action and structure-activity relationship studies of geobacillin I.Fundamental functionality: recent developments in understanding the structure-activity relationships of lantibiotic peptides.The dawning of a 'Golden era' in lantibiotic bioengineering.Increasing the success rate of lantibiotic drug discovery by Synthetic Biology.'Bac' to the future: bioengineering lantibiotics for designer purposes.Potentiating the Activity of Nisin against Escherichia coli.Multipronged approach for engineering novel peptide analogues of existing lantibiotics.Easy and rapid purification of highly active nisin.Antibacterial Peptides: Opportunities for the Prevention and Treatment of Dental Caries.Genome database mining for the discovery of novel lantibiotics.Employing the promiscuity of lantibiotic biosynthetic machineries to produce novel antimicrobials.Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.Antimicrobial Peptide-Conjugated Graphene Oxide Membrane for Efficient Removal and Effective Killing of Multiple Drug Resistant Bacteria.In vivo cluster formation of nisin and lipid II is correlated with membrane depolarization.
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Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Dissection and modulation of t ...... and by C-terminal truncation.
@en
type
label
Dissection and modulation of t ...... and by C-terminal truncation.
@en
prefLabel
Dissection and modulation of t ...... and by C-terminal truncation.
@en
P2093
P2860
P356
P1476
Dissection and modulation of t ...... and by C-terminal truncation.
@en
P2093
Anneke Kuipers
Arnold J M Driessen
Gert N Moll
Jenny Wierenga
Oscar P Kuipers
P2860
P304
P356
10.1128/AEM.01104-07
P407
P577
2007-07-27T00:00:00Z