The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors.
about
Apolipoprotein E receptors in the nervous systemThe Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor EnvironmentImpacts of tissue-type plasminogen activator (tPA) on neuronal survivalPhysiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous systemCellular prion protein participates in amyloid-β transcytosis across the blood-brain barrierLDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous systemLRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons.Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function.Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice.The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: a review of rtPA neurotoxicityProtein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway.Low-density lipoprotein receptor-related protein 1 (LRP1) regulates the stability and function of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor in neuronsLRP-1: functions, signaling and implications in kidney and other diseases.AAV-mediated overexpression of neuroserpin in the hippocampus decreases PSD-95 expression but does not affect hippocampal-dependent learning and memory.Exogenous t-PA administration increases hippocampal mature BDNF levels. plasmin- or NMDA-dependent mechanism?Metalloprotease meprin beta generates nontoxic N-terminal amyloid precursor protein fragments in vivo.Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration.Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor.Tissue and urokinase plasminogen activators instigate the degeneration of retinal ganglion cells in a mouse model of glaucoma.Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family.Stressed neurons protect themselves by a tissue-type plasminogen activator-mediated EGFR-dependent mechanism.Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.Phenolic compounds protect cultured hippocampal neurons against ethanol-withdrawal induced oxidative stress.LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.Role of plasminogen activator in spinal cord remodeling after spinal cord injury.One-Compound-Multi-Target: Combination Prospect of Natural Compounds with Thrombolytic Therapy in Acute Ischemic Stroke.Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity.Activation of peroxisome proliferator-activated receptor-δ attenuates glutamate-induced neurotoxicity in HT22 mouse hippocampal cells.Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina.NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity.Nerve growth factor-mediated regulation of low density lipoprotein receptor-related protein promoter activation.Adiponectin controls the apoptosis and the expression of tight junction proteins in brain endothelial cells through AdipoR1 under beta amyloid toxicity.LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair.Positive association of phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia.Amyloid-beta levels are significantly reduced and spatial memory defects are rescued in a novel neuroserpin-deficient Alzheimer's disease transgenic mouse model.
P2860
Q24607165-B0C7D7FC-8749-4FE8-B378-B794DDCE3B87Q26776179-5C1DF12F-9FC0-4809-8845-6D5649EF9E63Q26777261-E27250DB-7412-4405-89DE-3B8EA35A97EFQ26777276-CF738452-997B-4470-9C50-445E6ECC4A98Q28910485-F3FD753E-3971-4231-9818-21BAECACA0EBQ30408735-FBCFC390-E02C-459D-8785-AD57C0312689Q30541787-CA033840-325C-471D-B79A-3ACF83D7E788Q30667273-58CBA996-FEA8-4A3F-AD81-975CC2F734C1Q33369942-1E55A536-2300-4CE8-AF6C-E41CD23E8AF8Q34317977-28D29B78-D1DD-420F-B00D-ABAC5B0AD1DEQ34504984-DA36CA14-2B88-4AD5-B5BE-38BB5FE02157Q34589575-660D94B6-AE11-47FC-8541-CAEFA709ABB7Q34689361-8E1A83C0-7B0F-4B16-87ED-C4F1E7A32A3AQ34835060-6D2BDB58-3205-4C7F-A88A-4F1F4CF2090DQ35114530-93E3DCB0-79DD-4C45-9F73-986C9870B6EAQ35132128-E5E37CE6-5C41-40B8-9DBF-00EFBBDBD800Q35145029-BB85054A-FCA1-476E-8B74-841AB30BD591Q36101672-2450D4DC-9D05-4D1F-8DF6-1046D00DF845Q36125572-CF87E9B7-5232-40BB-9040-990B7F72E555Q36127093-DF895232-AD1D-4255-B2CE-20D7C968D884Q36386411-3176244F-D7C1-49D4-BC0C-5E11196DF81DQ36486210-5E89B783-3653-42BD-B656-39D54ECCCB5FQ36751280-F1E9344C-8563-4F07-9A33-56AC4BB123B2Q37048447-044902C6-CD63-44B1-AA86-37B187EBEB59Q37188265-00FCDB72-6CE1-4C1B-B504-7BC76FC966B0Q37333802-1B2EA15E-6B00-416A-988D-E141300CE805Q37570790-AA07AB7A-37EA-483B-90CA-CCD886879F2CQ37668019-91E5D8AC-8490-48D1-BDC5-FC0F42B08114Q38185972-2D25AB9A-5191-4D32-AD95-F99938B2FE90Q39369759-2E485589-D6A3-4631-851C-650D02E3C71FQ41161172-A66B600E-5862-489B-9F12-AD5B7719DBDAQ42032233-0986F9A4-B421-40C4-8621-B07418C54848Q43243037-BCE32221-B2E0-4D71-A078-1879B6E00679Q46115606-3DEFBDF6-6BE2-4328-8E5C-C4C54BD28FFBQ46288375-855F1499-39F9-4D85-8336-1D0714562434Q47130977-E920026A-BCD1-4186-9B7D-CD10D4659CCEQ48912789-2647C800-57BD-4300-8208-79302BE3756AQ49150181-EE1E4C2D-54F5-4900-8F98-7260EE69C49A
P2860
The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The functional role of the sec ...... -methyl-D-aspartate receptors.
@en
type
label
The functional role of the sec ...... -methyl-D-aspartate receptors.
@en
prefLabel
The functional role of the sec ...... -methyl-D-aspartate receptors.
@en
P2093
P2860
P356
P1476
The functional role of the sec ...... -methyl-D-aspartate receptors.
@en
P2093
Alexander Laatsch
Anne M Martin
Anton Roebroek
Christoph Kuhlmann
Claus U Pietrzik
Elaine Waldron
Heiko J Luhmann
Sascha Weggen
Sebastian Jaeger
Svenja Trossbach
P2860
P304
12004-12013
P356
10.1074/JBC.M707607200
P407
P577
2008-03-05T00:00:00Z