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Synthesis of 5-alkoxymethyl derivatives of 3'-amino-2',3'-dideoxyuridine and evaluation of their activity against HIV and cancerSynthesis of 3'-(4-nitroimidazol-1-yl)-2',3'-dideoxynucleosides of pyrimidine analogues and their biological evaluation against HIVVanillin formation from ferulic acid in Vanilla planifolia is catalysed by a single enzymeDe novo biosynthesis of vanillin in fission yeast (Schizosaccharomyces pombe) and baker's yeast (Saccharomyces cerevisiae)The biosynthetic gene cluster for the cyanogenic glucoside dhurrin in Sorghum bicolor contains its co-expressed vacuolar MATE transporterArabidopsis thaliana RGXT1 and RGXT2 encode Golgi-localized (1,3)-alpha-D-xylosyltransferases involved in the synthesis of pectic rhamnogalacturonan-II.A hydration study of (1-->4) and (1-->6) linked alpha-glucans by comparative 10 ns molecular dynamics simulations and 500-MHz NMR.The phosphorylation site in double helical amylopectin as investigated by a combined approach using chemical synthesis, crystallography and molecular modeling.Starch phosphorylation--maltosidic restrains upon 3'- and 6'-phosphorylation investigated by chemical synthesis, molecular dynamics and NMR spectroscopy.A combined nuclear magnetic resonance and molecular dynamics study of the two structural motifs for mixed-linkage beta-glucans: methyl beta-cellobioside and methyl beta-laminarabioside.Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme.First principles insight into the alpha-glucan structures of starch: their synthesis, conformation, and hydration.Phosphate esters in amylopectin clusters of potato tuber starch.Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum.Synthesis of the allelochemical alliarinoside present in garlic mustard (Alliaria petiolata), an invasive plant species in North America.Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants.Origin and evolution of transporter substrate specificity within the NPF family.Modulation of activity and substrate binding modes by mutation of single and double subsites +1/+2 and -5/-6 of barley alpha-amylase 1.In vitro Biochemical Characterization of All Barley Endosperm Starch Synthases.Lotus japonicus flowers are defended by a cyanogenic β-glucosidase with highly restricted expression to essential reproductive organs.Diversified glucosinolate metabolism: biosynthesis of hydrogen cyanide and of the hydroxynitrile glucoside alliarinoside in relation to sinigrin metabolism in Alliaria petiolata.Glucosinolate-related glucosides in Alliaria petiolata: sources of variation in the plant and different metabolism in an adapted specialist herbivore, Pieris rapae.Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore.Male-to-female transfer of 5-hydroxytryptophan glucoside during mating in Zygaena filipendulae (Lepidoptera).Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii.High throughput screening of starch structures using carbohydrate microarrays.Fusion of Ferredoxin and Cytochrome P450 Enables Direct Light-Driven Biosynthesis.Molecular interactions between barley and oat beta-glucans and phenolic derivatives.Genetic screening identifies cyanogenesis-deficient mutants of Lotus japonicus and reveals enzymatic specificity in hydroxynitrile glucoside metabolism.Tissue and cellular localization of individual beta-glycosidases using a substrate-specific sugar reducing assay.Synthesis of 4'-O-acetyl-maltose and alpha-D-galactopyranosyl-(1-->4)-D-glucopyranose for biochemical studies of amylose biosynthesis.The action of starch synthase II on 6"'-alpha-maltotriosyl-maltohexaose comprising the branch point of amylopectin.Chemical synthesis of methyl 6'-alpha-maltosyl-alpha-maltotrioside and its use for investigation of the action of starch synthase II.A facile protocol for direct conversion of unprotected sugars into phenyl 4,6-O-benzylidene-per-O-acetylated-1,2-trans-thioglycosides.Comparative study of small linear and branched alpha-glucans using size exclusion chromatography and static and dynamic light scattering.Glucosinolate engineering identifies a gamma-glutamyl peptidase.A recycling pathway for cyanogenic glycosides evidenced by the comparative metabolic profiling in three cyanogenic plant species.Diversification of an ancient theme: hydroxynitrile glucosides.Acid-catalysed rearrangement of glycosyl trichloroacetimidates: a novel route to glycosylamines.Characterization and expression profile of two UDP-glucosyltransferases, UGT85K4 and UGT85K5, catalyzing the last step in cyanogenic glucoside biosynthesis in cassava.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Mohammed S Motawia
@ast
Mohammed S Motawia
@en
Mohammed S Motawia
@es
Mohammed S Motawia
@sl
type
label
Mohammed S Motawia
@ast
Mohammed S Motawia
@en
Mohammed S Motawia
@es
Mohammed S Motawia
@sl
prefLabel
Mohammed S Motawia
@ast
Mohammed S Motawia
@en
Mohammed S Motawia
@es
Mohammed S Motawia
@sl
P106
P21
P31
P496
0000-0001-5582-9463