Replication-attenuated Human Adenoviral Type 4 vectors elicit capsid dependent enhanced innate immune responses that are partially dependent upon interactions with the complement system.
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Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy.Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factorTRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses.Vaccines within vaccines: the use of adenovirus types 4 and 7 as influenza vaccine vectors.Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo.Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors.CD46-mediated transduction of a species D adenovirus vaccine improves mucosal vaccine efficacy.Improving adenovirus based gene transfer: strategies to accomplish immune evasion.Exploitation of viral properties for intracellular delivery.An oncolytic adenovirus enhanced for toll-like receptor 9 stimulation increases antitumor immune responses and tumor clearance.Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and adenovirus (Ad5) immune mice.A preliminary and comparative evaluation of a novel Ad5 [E1-, E2b-] recombinant-based vaccine used to induce cell mediated immune responsesOptimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.
P2860
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P2860
Replication-attenuated Human Adenoviral Type 4 vectors elicit capsid dependent enhanced innate immune responses that are partially dependent upon interactions with the complement system.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Replication-attenuated Human A ...... ns with the complement system.
@en
type
label
Replication-attenuated Human A ...... ns with the complement system.
@en
prefLabel
Replication-attenuated Human A ...... ns with the complement system.
@en
P2093
P2860
P1433
P1476
Replication-attenuated Human A ...... ns with the complement system.
@en
P2093
Andrea Amalfitano
Daniel M Appledorn
Delila Serra
Oliver Glass
Timothy M Clay
Todd B Mendelson
Zachary C Hartman
P2860
P304
P356
10.1016/J.VIROL.2008.01.017
P407
P577
2008-02-15T00:00:00Z