PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).
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Calcium- and integrin-binding protein 1 regulates megakaryocyte ploidy, adhesion, and migrationPathobiology of secondary immune thrombocytopenia.MegakaryopoiesisThrombopoietin and hematopoietic stem cells.High doses of romiplostim induce proliferation and reduce proplatelet formation by human megakaryocytes.Protein kinase C δ deficiency enhances megakaryopoiesis and recovery from thrombocytopenia.Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.Adipose-Derived Mesenchymal Stem Cells (ADSCs) With the Potential to Ameliorate Platelet Recovery, Enhance Megakaryopoiesis, and Inhibit Apoptosis of Bone Marrow Cells in a Mouse Model of Radiation-Induced Thrombocytopenia.Insulin and glucagon regulate pancreatic α-cell proliferationbeta1-Integrin-collagen interaction suppresses FoxO3a by the coordination of Akt and PP2AMicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix.Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis.FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specificationPathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrixIntrinsic role of FoxO3a in the development of CD8+ T cell memory.Slug inhibits the proliferation and tumor formation of human cervical cancer cells by up-regulating the p21/p27 proteins and down-regulating the activity of the Wnt/β-catenin signaling pathway via the trans-suppression Akt1/p-Akt1 expression.Molecular mechanisms of thrombopoietin signaling.Thrombopoietin in normal and neoplastic stem cell development.The role of glycogen synthase kinase 3-β in immunity and cell cycle: implications in esophageal cancer.Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs.PKC-epsilon deficiency alters progenitor cell populations in favor of megakaryopoiesis.Zinc deficiency impairs the renewal of hippocampal neural stem cells in adult rats: involvement of FoxO3a activation and downstream p27(kip1) expression.CCN5/WISP-2 promotes growth arrest of triple-negative breast cancer cells through accumulation and trafficking of p27(Kip1) via Skp2 and FOXO3a regulation.Distinct roles of the mTOR components Rictor and Raptor in MO7e megakaryocytic cells.D-dencichine Regulates Thrombopoiesis by Promoting Megakaryocyte Adhesion, Migration and Proplatelet Formation.Megakaryocyte lineage development is controlled by modulation of protein acetylation.Staurosporine induces megakaryocytic differentiation through the upregulation of JAK/Stat3 signaling pathway.
P2860
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P2860
PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
PI3K/Akt/FOXO3a pathway contri ...... o via modulation of p27(Kip1).
@en
type
label
PI3K/Akt/FOXO3a pathway contri ...... o via modulation of p27(Kip1).
@en
prefLabel
PI3K/Akt/FOXO3a pathway contri ...... o via modulation of p27(Kip1).
@en
P2093
P356
P1433
P1476
PI3K/Akt/FOXO3a pathway contri ...... o via modulation of p27(Kip1).
@en
P2093
Amy E Geddis
Kenneth Kaushansky
Norma E Fox
Takafumi Nakao
P304
P356
10.4161/CC.7.2.5148
P577
2007-10-09T00:00:00Z