Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate
about
TRP channels in neurogastroenterology: opportunities for therapeutic interventionInternational Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyM1 receptors mediate cholinergic modulation of excitability in neocortical pyramidal neurons.Phosphoinositides: tiny lipids with giant impact on cell regulationOcular transient receptor potential channel function in health and disease.Kisspeptin excitation of GnRH neuronsComplex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels.Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugsIdentification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channelsPharmacology of store-operated calcium channelsGating of transient receptor potential melastatin 8 (TRPM8) channels activated by cold and chemical agonists in planar lipid bilayers.Voltage- and temperature-dependent activation of TRPV3 channels is potentiated by receptor-mediated PI(4,5)P2 hydrolysis.Identification of a membrane-targeting domain of the transient receptor potential canonical (TRPC)4 channel unrelated to its formation of a tetrameric structure.Trans-activation response (TAR) RNA-binding protein 2 is a novel modulator of transient receptor potential canonical 4 (TRPC4) proteinCell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cellsTRPC channels in smooth muscle cellsPhosphoinositides regulate ion channels.Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airwaysCooperative phosphoinositide and peptide binding by PSD-95/discs large/ZO-1 (PDZ) domain of polychaetoid, Drosophila zonulinCanonical transient receptor potential 4 and its small molecule modulators.Short isoforms of the cold receptor TRPM8 inhibit channel gating by mimicking heat action rather than chemical inhibitors.Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channelsSelective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.Update on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transportersTRPC4α and TRPC4β Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation.The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels.Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channelsmRNA expression of ion channels in GnRH neurons: subtype-specific regulation by 17β-estradiolTwo structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides.Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphateKisspeptin activation of TRPC4 channels in female GnRH neurons requires PIP2 depletion and cSrc kinase activation.Cross-talk between reproduction and energy homeostasis: central impact of estrogens, leptin and kisspeptin signalingPhospholipase C mediated modulation of TRPV1 channels.Submembraneous microtubule cytoskeleton: biochemical and functional interplay of TRP channels with the cytoskeleton.Transient receptor potential channels meet phosphoinositidesDeletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo.Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o.Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol.From guidance signals to movement: signaling molecules governing growth cone turning.Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels.
P2860
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P2860
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate
@en
type
label
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate
@en
prefLabel
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate
@en
P2093
P2860
P356
P1476
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate
@en
P2093
Alexander V Zholos
Jisen Tang
Ken-ichi Otsuguro
Marc Freichel
Michael X Zhu
Shigeo Ito
Veit Flockerzi
Volodymyr Tsvilovskyy
Yufang Tang
P2860
P304
10026-10036
P356
10.1074/JBC.M707306200
P407
P577
2008-01-29T00:00:00Z