about
Mechanism of protein tyrosine phosphatase 1B-mediated inhibition of leptin signallingGrowth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 techniqueGrowth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cellsGrowth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signalingJNK1 protects against glucolipotoxicity-mediated beta-cell apoptosisCRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent mannerDevelopmental expression of proprotein convertase 1/3 in the rat.STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma.Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protectionNuclear translocation and retention of growth hormone.Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicityCompartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neuronsCRFR1 activation protects against cytokine-induced β-cell death.Diabetes and suppressors of cytokine signaling proteins.Effects of growth hormone on glucose and fat metabolism in human subjects.Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas.Cytokines and beta-cell biology: from concept to clinical translation.Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells.Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus.Impact of fetal and neonatal environment on beta cell function and development of diabetes.Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents.Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.ID'ing a novel inhibitor of β-cell function, Id1.Surface-expressed insulin receptors as well as IGF-I receptors both contribute to the mitogenic effects of human insulin and its analogues.Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy.Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines.Deficient SOCS3 and SHP-1 expression in psoriatic T cells.Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells.Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells.IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells.Impact of fasting on growth hormone signaling and action in muscle and fat.Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells.IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line.Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells.Antitumorigenic effect of proteasome inhibitors on insulinoma cells.Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways.The role of signal transducer and activator of transcription 5 in the inhibitory effects of GH on adipocyte differentiation.Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Nils Billestrup
@ast
Nils Billestrup
@en
Nils Billestrup
@es
Nils Billestrup
@sl
type
label
Nils Billestrup
@ast
Nils Billestrup
@en
Nils Billestrup
@es
Nils Billestrup
@sl
prefLabel
Nils Billestrup
@ast
Nils Billestrup
@en
Nils Billestrup
@es
Nils Billestrup
@sl
P106
P1153
7003743719
P21
P31
P496
0000-0002-4968-8067