CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation.
about
Distinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cellsOverexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase.Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage.Influence of proline-rich inositol polyphosphate 5-phosphatase, on early development of fertilized mouse eggs, via inhibition of phosphorylation of Akt.CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity.Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication.CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar fociFodrin in centrosomes: implication of a role of fodrin in the transport of gamma-tubulin complex in brain.Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cellsNucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89.Screening of indeno[1,2-b]indoloquinones by MALDI-MS: a new set of potential CDC25 phosphatase inhibitors brought to light.Kizuna is a novel mitotic substrate for CDC25B phosphataseLats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targetsCell cycle and cell fate in the developing nervous system: the role of CDC25B phosphatase.A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death.CDC25B is involved in the centrosomal microtubule nucleation in two-cell stage mouse embryos.DNA damage-induced centrosome amplification occurs via excessive formation of centriolar satellites.RB in breast cancer: differential effects in estrogen receptor-positive and estrogen receptor-negative disease.Cdc25 phosphatases: differential regulation by ubiquitin-mediated proteolysis.Antileukaemic effect of PI3K-mTOR inhibitors in acute myeloid leukaemia-gene expression profiles reveal CDC25B expression as determinate of pharmacological effect.Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases.CHK1 as a therapeutic target to bypass chemoresistance in AML.Cytokinesis arrest and multiple centrosomes in B cell chronic lymphocytic leukaemia.
P2860
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P2860
CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
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2007年论文
@zh-cn
name
CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation.
@en
type
label
CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation.
@en
prefLabel
CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation.
@en
P1433
P1476
CDC25B involvement in the centrosome duplication cycle and in microtubule nucleation.
@en
P2093
Bernard Ducommun
Rose Boutros
P304
11557-11564
P356
10.1158/0008-5472.CAN-07-2415
P407
P577
2007-12-01T00:00:00Z