Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/Ras/ERK/NFkappaB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells.
about
Mammalian phospholipase D physiological and pathological rolesFunctional regulation of phospholipase D expression in cancer and inflammationCholine-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasisDesign of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.The IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells.Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA.Abnormal aquaporin-3 protein expression in hyperproliferative skin disordersDifferential regulation of cyclin D1 expression by protein kinase C α and ϵ signaling in intestinal epithelial cells.Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cellsPhospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancerGlaucine inhibits breast cancer cell migration and invasion by inhibiting MMP-9 gene expression through the suppression of NF-κB activation.Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.Phospholipase D1 has a pivotal role in interleukin-1β-driven chronic autoimmune arthritis through regulation of NF-κB, hypoxia-inducible factor 1α, and FoxO3aDefining the role of DAG, mitochondrial function, and lipid deposition in palmitate-induced proinflammatory signaling and its counter-modulation by palmitoleateG protein-coupled receptor connectivity to NF-kappaB in inflammation and cancer.Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells.Phosphatidic acid, phospholipase D and tumorigenesis.Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis.Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.Molecular targets in the discovery and development of novel antimetastatic agents: current progress and future prospects.NF-κB in colorectal cancer.Apoptosis signal-regulating kinase1 is inducible by protein kinase Cδ and contributes to phorbol ester-mediated G1 phase arrest through persistent JNK activation.Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 RegulationThe effect of ω-fatty acids on the expression of phospholipase A2 group 2A in human gastric cancer patients.5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis.Role of phospholipase D in regulation of testicular Leydig cell hyperplasia in Sprague-Dawley rats treated with di(2-ethylhexyl) phthalate.Functional role of phospholipase D (PLD) in di(2-ethylhexyl) phthalate-induced hepatotoxicity in Sprague-Dawley rats.Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation.Rebamipide abolishes Helicobacter pylori CagA-induced phospholipase D1 expression via inhibition of NFκB and suppresses invasion of gastric cancer cells.Autoregulation of phospholipase D activity is coupled to selective induction of phospholipase D1 expression to promote invasion of breast cancer cells.The progesterone receptor as a transcription factor regulates phospholipase D1 expression through independent activation of protein kinase A and Ras during 8-Br-cAMP-induced decidualization in human endometrial stromal cells.
P2860
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P2860
Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/Ras/ERK/NFkappaB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Phorbol ester up-regulates pho ...... cretion in colon cancer cells.
@en
type
label
Phorbol ester up-regulates pho ...... cretion in colon cancer cells.
@en
prefLabel
Phorbol ester up-regulates pho ...... cretion in colon cancer cells.
@en
P2093
P2860
P356
P1476
Phorbol ester up-regulates pho ...... cretion in colon cancer cells.
@en
P2093
Do Sik Min
Dong Woo Kang
Hyung Sik Kim
Mi Hee Park
Taeg Kyu Kwon
Won-Sang Park
Young Jun Lee
P2860
P304
P356
10.1074/JBC.M707416200
P407
P577
2007-12-15T00:00:00Z