Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis.
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Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSHProteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI.Fractional killing arises from cell-to-cell variability in overcoming a caspase activity thresholdKinetics in signal transduction pathways involving promiscuous oligomerizing receptors can be determined by receptor specificity: apoptosis induction by TRAIL.Post-translational modification of cardiac proteasomes: functional delineation enabled by proteomics.Proteasome inhibition and allogeneic hematopoietic stem cell transplantation: a reviewPrimitive quiescent CD34+ cells in chronic myeloid leukemia are targeted by in vitro expanded natural killer cells, which are functionally enhanced by bortezomibProteasomal regulation of caspase-8 in cancer cell apoptosisBortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction.The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8Caspase-8 as a therapeutic target in cancer.Apoptosis-modulating drugs for improved cancer therapy.The three Rs along the TRAIL: resistance, re-sensitization and reactive oxygen species (ROS).Caspase control: protagonists of cancer cell apoptosis.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-κB and the proteasome.IRE1alpha controls cyclin A1 expression and promotes cell proliferation through XBP-1.Bortezomib reverses the proliferative and antiapoptotic effect of neuropeptides on prostate cancer cells.Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link.
P2860
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P2860
Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Proteasome inhibition blocks c ...... h receptor-mediated apoptosis.
@en
type
label
Proteasome inhibition blocks c ...... h receptor-mediated apoptosis.
@en
prefLabel
Proteasome inhibition blocks c ...... h receptor-mediated apoptosis.
@en
P2093
P356
P1433
P1476
Proteasome inhibition blocks c ...... h receptor-mediated apoptosis.
@en
P2093
Jeffery A Thorpe
Perry A Christian
Steven R Schwarze
P304
P356
10.1002/PROS.20706
P577
2008-02-01T00:00:00Z