A second nonstructural protein functions in the regulation of alphavirus negative-strand RNA synthesis.
about
Alphavirus RNA synthesis and non-structural protein functionsHigh-resolution functional mapping of the venezuelan equine encephalitis virus genome by insertional mutagenesis and massively parallel sequencingRole for nsP2 proteins in the cessation of alphavirus minus-strand synthesis by host cellsGenesis of Sindbis virus by in vivo recombination of nonreplicative RNA precursorsNonhomologous RNA-RNA recombination events at the 3' nontranslated region of the Sindbis virus genome: hot spots and utilization of nonviral sequencesA novel viral RNA species in Sindbis virus-infected cellsRegulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesisGenetic analysis of the nsP3 region of Sindbis virus: evidence for roles in minus-strand and subgenomic RNA synthesisATPase and GTPase activities associated with Semliki Forest virus nonstructural protein nsP2Molecular cloning, overproduction, purification and biochemical characterization of the p39 nsp2 protease domains encoded by three alphavirusesThe alphaviruses: gene expression, replication, and evolutionAnalysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processingFunctional analysis of nsP3 phosphoprotein mutants of Sindbis virus.Alphavirus minus-strand RNA synthesis: identification of a role for Arg183 of the nsP4 polymerase.Alphavirus minus-strand synthesis and persistence in mouse embryo fibroblasts derived from mice lacking RNase L and protein kinase R.Ribosomal protein S6 associates with alphavirus nonstructural protein 2 and mediates expression from alphavirus messagesEvidence that the potyvirus P1 proteinase functions in trans as an accessory factor for genome amplificationSindbis virus RNA-negative mutants that fail to convert from minus-strand to plus-strand synthesis: role of the nsP2 protein.Purification, crystallization and X-ray diffraction analysis of the C-terminal protease domain of Venezuelan equine encephalitis virus nsP2Alphavirus nsP3 functions to form replication complexes transcribing negative-strand RNASelection of RNA replicons capable of persistent noncytopathic replication in mammalian cells.Template-dependent initiation of Sindbis virus RNA replication in vitro.Replicon vectors derived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells.Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1.Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis.Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2.Nonstructural Proteins of Alphavirus-Potential Targets for Drug Development.Timeliness of proteolytic events is prerequisite for efficient functioning of the alphaviral replicase.
P2860
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P2860
A second nonstructural protein functions in the regulation of alphavirus negative-strand RNA synthesis.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
A second nonstructural protein ...... negative-strand RNA synthesis.
@en
type
label
A second nonstructural protein ...... negative-strand RNA synthesis.
@en
prefLabel
A second nonstructural protein ...... negative-strand RNA synthesis.
@en
P2860
P1433
P1476
A second nonstructural protein ...... negative-strand RNA synthesis
@en
P2093
D L Sawicki
S G Sawicki
P2860
P304
P407
P577
1993-06-01T00:00:00Z