MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
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Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain DiseasesmTOR-dependent signalling in Alzheimer's diseaseCaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell deathCadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell deathThe mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsyActivation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's diseaseN-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain.Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network.PRAK interacts with DJ-1 and prevents oxidative stress-induced cell death.Environmental cadmium and breast cancer risk.Dual regulation of cadmium-induced apoptosis by mTORC1 through selective induction of IRE1 branches in unfolded protein response.Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.Salidroside Protects against Cadmium-Induced Hepatotoxicity in Rats via GJIC and MAPK PathwaysRapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathwaysThe MAPK and PI3K pathways mediate CNTF-induced neuronal survival and process outgrowth in hypothalamic organotypic cultures.Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cellsCelastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway.Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium.Sensitivity of neural stem cell survival, differentiation and neurite outgrowth within 3D hydrogels to environmental heavy metalsRapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis.Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site.Ras and rheb signaling in survival and cell deathCadmium and its neurotoxic effectsBAFF activates Erk1/2 promoting cell proliferation and survival by Ca2+-CaMKII-dependent inhibition of PP2A in normal and neoplastic B-lymphoid cells.ERK and cell death: cadmium toxicity, sustained ERK activation and cell death.Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?Cadmium and cellular signaling cascades: interactions between cell death and survival pathways.Neuro- and nephrotoxicity of subchronic cadmium chloride exposure and the potential chemoprotective effects of selenium nanoparticles.mTOR Signaling in Parkinson's Disease.Cadmium impairs the survival and proliferation of cultured adult subventricular neural stem cells through activation of the JNK and p38 MAP kinases.Cadmium induces PC12 cells apoptosis via an extracellular signal-regulated kinase and c-Jun N-terminal kinase-mediated mitochondrial apoptotic pathway.Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway.[6]-shogaol attenuates neuronal apoptosis in hydrogen peroxide-treated astrocytes through the up-regulation of neurotrophic factors.Mechanisms of MPP⁺-induced PC12 cell apoptosis via reactive oxygen species.Modulation of oxidative stress and tau phosphorylation by the mTOR activator phosphatidic acid in SH-SY5Y cells.Cadmium ions promote monocytic differentiation of human leukemia HL-60 cells treated with 1α,25-dihydroxyvitamin D3.IL-2, IL-4, IFN-γ or TNF-α enhances BAFF-stimulated cell viability and survival by activating Erk1/2 and S6K1 pathways in neoplastic B-lymphoid cells.
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MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
@en
type
label
MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
@en
prefLabel
MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
@en
P2860
P1476
MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis.
@en
P2093
P2860
P304
P356
10.1111/J.1471-4159.2007.05133.X
P407
P577
2007-11-16T00:00:00Z