Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells.
about
The PD-1 pathway in tolerance and autoimmunityCentral role of defective interleukin-2 production in the triggering of islet autoimmune destructionT cell costimulatory and coinhibitory pathways in vascular inflammatory diseasesWhere CD4+CD25+ T reg cells impinge on autoimmune diabetesTargeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes.Immunopathogenesis of thyroid eye disease: emerging paradigmsTh17 cells and regulatory T cells in elite control over HIV and SIV.Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic isletsB7-1 mediated costimulation regulates pancreatic autoimmunity.Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion.Impaired dendritic cell function in a spontaneous autoimmune polyneuropathy.Spontaneous allograft tolerance in B7-deficient mice independent of preexisting endogenous CD4+CD25+ regulatory T-cells.The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases.Breakdown in peripheral tolerance in type 1 diabetes in mice and humansThe 15N and 46R Residues of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Enhance Regulatory T Lymphocytes ProliferationT cells in the control of organ-specific autoimmunityInsulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.The stages of type 1A diabetes.PI3Kγ Deficient NOD-Mice Are Protected from Diabetes by Restoring the Balance of Regulatory to Effector-T-Cells.Imbalance of regulatory T cells in human autoimmune diseases.Role of bioactivation in drug-induced hypersensitivity reactions.Coinhibitory T-cell signaling in islet allograft rejection and tolerance.Adaptive immunity in atherogenesis: new insights and therapeutic approaches.Current and future immunomodulation strategies to restore tolerance in autoimmune diseases.Regulatory T-cell physiology and application to treat autoimmunity.Regulatory T cells and systemic lupus erythematosus.Vaccine-based approaches to squamous cell carcinoma of the head and neck.Spontaneous development of a pancreatic exocrine disease in CD28-deficient NOD mice.Plasmacytoid precursor dendritic cells from NOD mice exhibit impaired function: are they a component of diabetes pathogenesis?CD28 costimulation is essential for human T regulatory expansion and functionCo-stimulatory and Co-inhibitory Pathways in Autoimmunity.The net effect of costimulatory blockers is dependent on the subset and activation status of the autoreactive T cells.Targeting regulatory T cells in the treatment of type 1 diabetes mellitus.Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis.CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell responseT-cell costimulation and coinhibition in atherosclerosis.Development of monoclonal antibodies to detect bovine FOXP3 in PBMCs exposed to a staphylococcal superantigenGenetic and Molecular Basis of QTL of Diabetes in Mouse: Genes and PolymorphismsA novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy.
P2860
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P2860
Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Costimulation controls diabete ...... ogenic and regulatory T cells.
@en
type
label
Costimulation controls diabete ...... ogenic and regulatory T cells.
@en
prefLabel
Costimulation controls diabete ...... ogenic and regulatory T cells.
@en
P2093
P2860
P356
P1476
Costimulation controls diabete ...... hogenic and regulatory T cells
@en
P2093
Gregory L Szot
Heather L Thompson
Hélène Bour-Jordan
Jeffrey A Bluestone
Matthew R Bernhard
P2860
P304
P356
10.1172/JCI200420483
P407
P577
2004-10-01T00:00:00Z