An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein.
about
HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradationThe great escape: viral strategies to counter BST-2/tetherinThe interferon response inhibits HIV particle production by induction of TRIM22The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to VpuSpecies-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2Rab7A is required for efficient production of infectious HIV-1Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomainBroad-spectrum inhibition of retroviral and filoviral particle release by tetherinCell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factorsThe restriction factors of human immunodeficiency virusHIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanismsDifferential effects of human immunodeficiency virus type 1 Vpu on the stability of BST-2/tetherinAntiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteractionVpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanismHIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomesInhibition of Lassa and Marburg virus production by tetherinRemodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceThe Role of Cytokines and Chemokines in Filovirus InfectionVpu Protein: The Viroporin Encoded by HIV-1Evolution of foamy viruses: the most ancient of all retrovirusesHIV restriction in quiescent CD4⁺ T cellsThree-Dimensional Structural Characterization of HIV-1 Tethered to Human Cells.Characterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-ComplementationStructural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformationsMechanism of HIV-1 virion entrapment by tetherinInterferon-induced tetherin restricts vesicular stomatitis virus release in neuronsThe KT Jeang Retrovirology prize 2015: Paul BieniaszIntrinsic cellular defenses against human immunodeficiency virusesCounteraction of the multifunctional restriction factor tetherinVpu and BST2: Still Not There Yet?The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu proteinPandemic HIV-1 Vpu overcomes intrinsic herd immunity mediated by tetherin.Vpu-Mediated Counteraction of Tetherin Is a Major Determinant of HIV-1 Interferon Resistance.Modulation of HIV-1-host interaction: role of the Vpu accessory proteinHIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef.Tetherin restricts direct cell-to-cell infection of HIV-1.Ultra structural characterisation of tetherin - a protein capable of preventing viral release from the plasma membraneSpecies-specific activity of HIV-1 Vpu and positive selection of tetherin transmembrane domain variantsMutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion.Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.
P2860
Q21089617-3FAE9F5D-A103-439E-A602-34808FED8CFFQ21090506-FFC68C95-D2FF-42E3-9F23-E1BFD9766B84Q21131598-5C04A1D8-8928-4AE2-89FC-21A566C1C42EQ21245050-2B52DC15-1C16-4C6E-BCC0-91B43B0E4D4EQ21559418-38B38D39-087A-4673-BEE1-5BED4184AA6BQ24296650-44A89F83-2183-4566-B7CD-3718501B8DCCQ24306855-261B51A6-3912-4209-BCAE-81CC041E295DQ24318564-947E3A44-FC20-4EE9-9C92-F5E07DA3BA1FQ24604018-7842779D-B0D3-4A32-9C5A-D674E5403186Q24605108-BA58DC54-D2A3-499A-829B-F891FBE4AC30Q24619066-74EEB03D-88F3-433C-B805-5D15AFE4983CQ24629504-D67823B3-6BB3-488B-B407-8F5D3B0EC511Q24635271-636783C0-972A-4744-9DCE-EA6C51E040B7Q24644811-E42D9EFF-01AA-4FEC-B45D-D0B05BD6D649Q24646984-08657B6B-9342-442F-B92A-9D20485A1F26Q24652263-16A607D7-EBDB-4224-A065-DE4E3586F834Q26767362-F35C5168-B69D-43E6-9090-D15AFE9EC8D6Q26778003-9AC26710-8ACC-4852-B359-6E3CCF90C574Q26801489-AFBCCD2A-8A29-4A5F-BA09-C8337F0EF0E7Q26852372-DAC78C94-9FCC-47F0-978F-FFADF0776BF6Q26995784-E80A97A3-5C3A-447D-900A-08D76CDF2D5DQ27321247-A2313CF9-0F8D-46F3-85E8-1FCFC4080F8EQ27490303-A0C9EB62-49EC-401C-B7EB-723B7FEB43F0Q27664759-A32FE708-425A-4FE5-95A9-491A160FA48AQ28534707-8C77DD0D-C7B2-41E6-987A-E4003B364839Q28585561-A72B5176-48DA-4193-A049-7762E78C59A6Q28606741-5CAD9CB7-B026-4386-83FA-51A350462FA2Q28659575-32087380-C492-43E6-89F5-D0CA36D17365Q28659945-2D650884-5EF2-42F4-AB34-692979A4C70EQ28730708-C89AD9B7-6E21-4F21-A59F-CA142F950366Q29619540-321B9AF5-1B12-4F7D-90DE-8B1D33764CD0Q30376824-F012689D-ED69-4A94-9016-A8B637CFE37DQ30391895-D6831966-FD61-470A-844C-44E43412D596Q30397761-5385BF84-8ABC-4267-AC8B-429A305E6032Q30410687-6C910D7A-0FF0-460F-B7F7-5279333E5163Q30497822-3D13BA91-C832-4FB5-BE31-3DC70623E717Q31034125-3C4FF95B-3571-45D3-8AA7-F74BCE020837Q33408799-28BBAFE2-EC7D-4437-BE06-CE08303368A3Q33450556-C427ADA6-B657-4F53-A688-5E6D52F2C8C4Q33455505-5205EBCB-C42F-43DF-BAC0-C22A4B8986BB
P2860
An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
An interferon-alpha-induced te ...... cted by the HIV-1 Vpu protein.
@en
type
label
An interferon-alpha-induced te ...... cted by the HIV-1 Vpu protein.
@en
prefLabel
An interferon-alpha-induced te ...... cted by the HIV-1 Vpu protein.
@en
P2093
P2860
P1433
P1476
An interferon-alpha-induced te ...... cted by the HIV-1 Vpu protein.
@en
P2093
Paul D Bieniasz
Stuart J D Neil
Virginie Sandrin
Wesley I Sundquist
P2860
P304
P356
10.1016/J.CHOM.2007.08.001
P577
2007-09-01T00:00:00Z