Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors.
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Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cellsYAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferationPediatric primary central nervous system germ cell tumors of different prognosis groups show characteristic miRNome traits and chromosome copy number variations.Expression of microRNAs in basal cell carcinoma.β-Arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors.MicroRNA gene expression signatures in the developing neural tubeOncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activationIndole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells.An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation.The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells.Activation of the hedgehog-signaling pathway in human cancer and the clinical implications.Hedgehog signaling: networking to nurture a promalignant tumor microenvironment.Targeted treatment for sonic hedgehog-dependent medulloblastoma.YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.Primary Cilia and Coordination of Receptor Tyrosine Kinase (RTK) and Transforming Growth Factor β (TGF-β) Signaling.mTOR pathway as a potential target in a subset of human medulloblastoma.Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network.WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastomaDivergent functions for eIF4E and S6 kinase by sonic hedgehog mitogenic signaling in the developing cerebellumMitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.Cooperation between Shh and IGF-I in promoting myogenic proliferation and differentiation via the MAPK/ERK and PI3K/Akt pathways requires Smo activityNutrient-driven O-GlcNAc in proteostasis and neurodegeneration.Lkb1 regulates granule cell migration and cortical folding of the cerebellar cortex.Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells.
P2860
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P2860
Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Insulin receptor substrate 1 i ...... cerebellar neural precursors.
@en
type
label
Insulin receptor substrate 1 i ...... cerebellar neural precursors.
@en
prefLabel
Insulin receptor substrate 1 i ...... cerebellar neural precursors.
@en
P2093
P2860
P356
P1433
P1476
Insulin receptor substrate 1 i ...... cerebellar neural precursors.
@en
P2093
Africa Fernandez-L
Anna Marie Kenney
Dane Ohlosson Campbell
Lori Anne Mainwaring
Susana R Parathath
P2860
P304
P356
10.1242/DEV.022871
P407
P577
2008-08-28T00:00:00Z