Modulation of human platelet adenylate cyclase by prostacyclin (PGX).
about
Platelet signaling: a complex interplay between inhibitory and activatory networksEighth Gaddum Memorial Lecture. University of London Institute of Education, December 1980. Biological importance of prostacyclinProstaglandin I2 and the nitric oxide donor molsidomine have synergistic effects on thromboresistance in man.Functional and ligand binding studies suggest heterogeneity of platelet prostacyclin receptorsNovel platelet-agglutinating protein from a thrombotic thrombocytopenic purpura plasma.Pharmacology of endothelium-derived nitric oxide and nitrovasodilators.Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled.Iloprost-induced translocation of a 23-kDa protein that is recognized by a Gs alpha antiserumThe prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling.Dipyridamole increases red cell deformability.Potential therapeutic applications of aspirin and other cyclo-oxygenase inhibitors.Thromboxane synthase is preferentially conserved in activated mouse peritoneal macrophages.Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.Inhibition of human platelet thromboxane synthetase by 9,11-azoprosta-5,13-dienoic acid.Inhibitors of protein and RNA synthesis cause a rapid block in prostaglandin production at the prostaglandin synthase stepProstaglandin I2 (prostacyclin).Prostacyclin releases endothelium-derived relaxing factor and potentiates its action in coronary arteries of the pig.The prostanoids in hemostasis and thrombosis: a review.Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.Segregation of discrete GS alpha-mediated responses that accompany homologous or heterologous desensitization in two related somatic hybrids.Platelet release reaction and aggregation induced by canatoxin, a convulsant protein: evidence for the involvement of the platelet lipoxygenase pathway.12(S)-HETrE, a 12-Lipoxygenase Oxylipin of Dihomo-γ-Linolenic Acid, Inhibits Thrombosis via Gαs Signaling in PlateletsAnti-aggregatory effect of prostacyclin (PGI2) in vivo.Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: prostanoid structure-activity relationshipsDesensitization of prostacyclin receptors in a neuronal hybrid cell line.Actin filament content and organization in unstimulated plateletsRole of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium.Persistence of increased platelet cyclic AMP induced by prostaglandin E1 after removal of the hormone.Role of myosin phosphorylation in contractility of a platelet aggregate.Inhibition of idiosyncratic reactions to aspirin in asthmatic patients by clemastine.Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment.Release of adenosine from human neutrophils stimulated by platelet activating factor, leukotriene B(4) and opsonized zymosan.Nobel lecture. Adventures and excursions in bioassay--the stepping stones to prostacyclin.Platelets, endothelium-dependent responses and atherosclerosis.Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets.Prostacyclin biosynthesis in cultured vascular endothelium is limited by deactivation of cyclooxygenaseRole of hydrogen peroxide in the neutrophil-mediated release of prostacyclin from cultured endothelial cellsAbnormal platelet response to thromboxane A2.Selective binding site for [3H]prostacyclin on platelets.Recovery of endothelial cell prostacyclin production after inhibition by low doses of aspirin.
P2860
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P2860
Modulation of human platelet adenylate cyclase by prostacyclin (PGX).
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
1977年论文
@zh
1977年论文
@zh-cn
name
Modulation of human platelet adenylate cyclase by prostacyclin (PGX).
@en
type
label
Modulation of human platelet adenylate cyclase by prostacyclin (PGX).
@en
prefLabel
Modulation of human platelet adenylate cyclase by prostacyclin (PGX).
@en
P2093
P1433
P1476
Modulation of human platelet adenylate cyclase by prostacyclin (PGX).
@en
P2093
P304
P356
10.1016/0090-6980(77)90018-1
P577
1977-03-01T00:00:00Z