BAG-1 associates with Hsc70.Tau complex and regulates the proteasomal degradation of Tau protein.
about
Short peptides derived from the BAG-1 C-terminus inhibit the interaction between BAG-1 and HSC70 and decrease breast cancer cell growthThe ubiquitin proteasomal system: a potential target for the management of Alzheimer's diseaseTau and tauopathiesHeat shock proteins in neurodegenerative disorders and agingThioflavin S (NSC71948) interferes with Bcl-2-associated athanogene (BAG-1)-mediated protein-protein interactions.The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism.BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity.Mechanisms of tau-induced neurodegeneration.Heat shock protein 70 (hsp70) as an emerging drug target.The BAG-1 isoform BAG-1M regulates keratin-associated Hsp70 chaperoning of aPKC in intestinal cells during activation of inflammatory signaling.BAG1: the guardian of anti-apoptotic proteins in acute myeloid leukemia.Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone.Tau in Alzheimer disease and related tauopathies.Macronutrient deprivation modulates antigen trafficking and immune recognition through HSC70 accessibility.Management of cytoskeleton architecture by molecular chaperones and immunophilins.Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies.Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex.Subcellular distribution of non-muscle myosin IIb is controlled by FILIP through Hsc70Molecular chaperones as regulators of cell death.Hsp70 structure, function, regulation and influence on yeast prions.O-GlcNAc cycling: implications for neurodegenerative disorders.The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule.Chaperone signalling complexes in Alzheimer's disease.Protein Quality Control by Molecular Chaperones in Neurodegeneration.Protein homeostasis, aging and Alzheimer's disease.Biochemistry and cell biology of tau protein in neurofibrillary degenerationDegradation of tau protein by autophagy and proteasomal pathways.Hsp70 protein complexes as drug targets.Interaction between misfolded PrP and the ubiquitin-proteasome system in prion-mediated neurodegeneration.Opportunities and challenges for molecular chaperone modulation to treat protein-conformational brain diseasesCellular factors modulating the mechanism of tau protein aggregation.Molecular chaperones and neuronal proteostasis.Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.The fine-tuning of proteolytic pathways in Alzheimer's disease.Bcl-2-associated athanogene 2 prevents the neurotoxicity of MPP+ via interaction with DJ-1.Therapeutic Strategies for Restoring Tau Homeostasis.The presence of extracellular matrix alters the chondrocyte response to endoplasmic reticulum stress.Ethanol enhances tau accumulation in neuroblastoma cells that inducibly express tau.Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics.β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.
P2860
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P2860
BAG-1 associates with Hsc70.Tau complex and regulates the proteasomal degradation of Tau protein.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
BAG-1 associates with Hsc70.Ta ...... al degradation of Tau protein.
@en
type
label
BAG-1 associates with Hsc70.Ta ...... al degradation of Tau protein.
@en
prefLabel
BAG-1 associates with Hsc70.Ta ...... al degradation of Tau protein.
@en
P2860
P356
P1476
BAG-1 associates with Hsc70.Ta ...... mal degradation of Tau protein
@en
P2093
Evan Elliott
Irith Ginzburg
P2860
P304
37276-37284
P356
10.1074/JBC.M706379200
P407
P577
2007-10-22T00:00:00Z