An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene.
about
Architectural roles of multiple chromatin insulators at the human apolipoprotein gene clusterA chromatin insulator-like element in the herpes simplex virus type 1 latency-associated transcript region binds CCCTC-binding factor and displays enhancer-blocking and silencing activities.Emerging epigenetic mechanisms of long non-coding RNAsInsulators: exploiting transcriptional and epigenetic mechanismsMaternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo developmentWidespread transcription at neuronal activity-regulated enhancersA weakened transcriptional enhancer yields variegated gene expressionCTCF genomic binding sites in Drosophila and the organisation of the bithorax complexTargeted deletion of multiple CTCF-binding elements in the human C-MYC gene reveals a requirement for CTCF in C-MYC expression.Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sitesTranscription of the herpes simplex virus 1 genome during productive and quiescent infection of neuronal and nonneuronal cells.CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin.Chromatin loop formation in the β-globin locus and its role in globin gene transcriptionChromatin boundaries require functional collaboration between the hSET1 and NURF complexes.Beta-globin intergenic transcription and histone acetylation dependent on an enhancer.Higher-order chromatin regulation and differential gene expression in the human tumor necrosis factor/lymphotoxin locus in hepatocellular carcinoma cellsEnhancer and promoter interactions-long distance calls.An RNA-independent linkage of noncoding transcription to long-range enhancer function.A facilitated tracking and transcription mechanism of long-range enhancer function.Influence of a CTCF-Dependent Insulator on Multiple Aspects of Enhancer-Mediated Chromatin OrganizationNucleosome and transcription activator antagonism at human beta-globin locus control region DNase I hypersensitive sites.Remote control of gene transcription.Chromatin domain boundaries: insulators and beyond.Organizing the genome: enhancers and insulators.Genetic and epigenetic mechanisms of gene regulation during lens development.USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.CTCF occupation of the herpes simplex virus 1 genome is disrupted at early times postreactivation in a transcription-dependent manner.We gather together: insulators and genome organization.Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome.Promoter cross-talk via a shared enhancer explains paternally biased expression of Nctc1 at the Igf2/H19/Nctc1 imprinted locus.Enhancer blocking activity of the insulator at H19-ICR is independent of chromatin barrier establishment.Chromatin loops in gene regulation.Epigenetics of beta-globin gene regulationChromatin insulators: regulatory mechanisms and epigenetic inheritance.The use of chromatin insulators to improve the expression and safety of integrating gene transfer vectorsThe insulator protein CTCF binding sites in the orf73/LANA promoter region of herpesvirus saimiri are involved in conferring episomal stability in latently infected human T cells.Regulatory Domains and Their Mechanisms.A Model System in S2 Cells to Test the Functional Activities of Drosophila Insulators.Effects of sister chromatid cohesion proteins on cut gene expression during wing development in Drosophila.An insulator embedded in the chicken α-globin locus regulates chromatin domain configuration and differential gene expression.
P2860
Q24309356-671C0F7D-6342-4FEE-8F69-D0A202EFC1BBQ24544258-7194B1B3-73A4-4757-A043-F9FF9292B63AQ27002577-A9E7E321-2D67-49EC-B68A-ABFE90BE663BQ28257767-E361EBEA-2AF1-476A-8062-8213748C5FAEQ28586603-B7A40F31-6295-4F34-832D-CFC2E0667213Q29614330-881E81FE-BE56-49A7-AA3A-C87D272F5302Q33267292-9A3085A4-77AA-41B7-A8A8-B5BE7CAEAC10Q33290220-900A0C69-F596-4038-A1A2-00584B459BC6Q33476843-86A062E5-339D-42E9-8BD3-4DD31004A207Q33559752-5AE98A98-D505-4174-9646-4BA72CD78C66Q33743904-CA39D542-CA0B-4743-9EDD-27E801D48CECQ34021284-348A0843-50AB-4A97-846D-8093BFF9A390Q34276131-7837D663-4581-4CE4-86F1-7733D2A38173Q35153806-6D1041B7-9A03-4206-93F1-B169DEF9A7BCQ35856822-DD2A9175-2463-4C9B-B8F8-C59B43BFA844Q35867922-FF1AEC21-D3AF-4DE8-8959-63A65F497C2CQ35928743-A4B70138-5445-43EA-BCFE-302B930BCEC9Q35943957-938ABC4A-452C-4D85-B3AD-C94134A60E50Q36059486-C2EFD4B9-176D-47F6-95C1-7252CD9716E8Q36070020-5C54E1EF-21A5-40EB-92C1-E226FAB226AFQ36082870-11AFB045-2C38-41B4-85C3-FEB956FB09E6Q36088911-6A15581A-620C-41F4-B680-6B4413276C7BQ36109317-B4EC85D4-D783-400E-9D6A-37F31CF17B53Q36226173-D89945C0-4AC7-46B0-B465-1A1909F5E5DDQ36262540-24C0CBC5-7868-4DDB-9AC0-D224D14068EBQ36315893-E4F5C8EB-22D2-4E28-9F47-2DA5D01A2EE9Q36397366-2086C919-2D01-4D3F-806F-57C44141BC29Q36407771-EF754616-2E29-45D5-A6C1-67F7EE4F7F01Q36482074-41B4C725-DA62-4566-9874-BE72ED06C9BDQ36559183-365E58BE-C1CC-4E6A-94AA-16BDDBF088D8Q36711228-062FC700-8229-4A9C-BCEC-1C4DFAC1E00EQ37233805-2E95DA02-AB15-424D-B9C4-4F18C179FF3EQ37257146-4B460D0B-A07B-4A46-9710-9E7DD513CB7AQ37292727-F0433502-7354-4708-A16F-493A7CCA6992Q37830029-7C7FC386-7CDB-4E31-AD0D-1C20AFF1F096Q38329891-43187A2C-4E17-4A16-BDBC-023D5112998BQ38641320-0D253DA2-5D8B-4E92-890F-4A22D0255F08Q38800534-D8BBE308-ACFA-40D0-8DAE-CC21B63EC9F5Q39089095-7F1CC006-0BE0-4C61-B36D-15E236FE124BQ39660123-2AB811DE-9F00-4046-B2DC-E1533354BD62
P2860
An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
An insulator blocks spreading ...... between an enhancer and gene.
@en
type
label
An insulator blocks spreading ...... between an enhancer and gene.
@en
prefLabel
An insulator blocks spreading ...... between an enhancer and gene.
@en
P2860
P356
P1476
An insulator blocks spreading ...... between an enhancer and gene.
@en
P2093
P2860
P304
P356
10.1093/NAR/GKH832
P577
2004-09-15T00:00:00Z