Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression.
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Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and functionPax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretionA genome-wide association study identifies susceptibility variants for type 2 diabetes in Han ChineseRelative roles of the different Pax6 domains for pancreatic alpha cell development.Engineering an L-cell line that expresses insulin under the control of the glucagon-like peptide-1 promoter for diabetes treatment.Functional redundancy of two Pax-like proteins in transcriptional activation of cyst wall protein genes in Giardia lamblia.A novel pax-like protein involved in transcriptional activation of cyst wall protein genes in Giardia lamblia.Evaluation of insulin expression and secretion in genetically engineered gut K and L-cellsMicroRNA expression in alpha and beta cells of human pancreatic islets.Microarray analysis of novel candidate genes responsible for glucose-stimulated insulin secretion in mouse pancreatic β cell line MIN6.Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in miceDICER Inactivation Identifies Pancreatic β-Cell "Disallowed" Genes Targeted by MicroRNAs.Pax6 regulates the proglucagon processing enzyme PC2 and its chaperone 7B2.Multiple functions of Maf in the regulation of cellular development and differentiation.MafA and MafB activity in pancreatic β cells.Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in α-cell differentiation, glucagon biosynthesis and secretion.Glucagon: the renewal of an old hormone in the pathophysiology of diabetes.Role of transcription factors in the transdifferentiation of pancreatic islet cells.Glucose-dependent downregulation of glucagon gene expression mediated by selective interactions between ALX3 and PAX6 in mouse alpha cells.The New Biology and Pharmacology of Glucagon.The L-cell isolation from heterogonous population of intestinal cell line using antibiotic selection method.Role of large MAF transcription factors in the mouse endocrine pancreas.MafB is critical for glucagon production and secretion in mouse pancreatic α-cells in vivo.c-Maf increases apoptosis in peripheral CD8 cells by transactivating Caspase 6.Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation.
P2860
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P2860
Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Pax-6 and c-Maf functionally i ...... mote glucagon gene expression.
@en
type
label
Pax-6 and c-Maf functionally i ...... mote glucagon gene expression.
@en
prefLabel
Pax-6 and c-Maf functionally i ...... mote glucagon gene expression.
@en
P2093
P2860
P356
P1476
Pax-6 and c-Maf functionally i ...... mote glucagon gene expression.
@en
P2093
Aline Mamin
Isabelle Avril
Jacques Philippe
Yvan Gosmain
P2860
P304
35024-35034
P356
10.1074/JBC.M702795200
P407
P577
2007-09-27T00:00:00Z