about
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzymeVariation in FTO contributes to childhood obesity and severe adult obesityGenome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populationsDysfunction of lipid sensor GPR120 leads to obesity in both mouse and humanTwo new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groupsEffects of obesity on human sexual development.Concordance of bioactive vs. total immunoreactive serum leptin levels in children with severe early onset obesityGenetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity.TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes.Harmonization of growth hormone measurements with different immunoassays by data adjustment.Impact of metabolic regulators on the expression of the obesity associated genes FTO and NAMPT in human preadipocytes and adipocytesEffects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children.Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.Evaluation of A2BP1 as an obesity gene.The LIFE child study: a life course approach to disease and health.The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion.Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans.Direct evidence of brown adipocytes in different fat depots in children.Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolismNew predictors of the metabolic syndrome in children--role of adipocytokines.Adipocytes and adipose tissue.Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity.Nampt: linking NAD biology, metabolism and cancer.Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism.Preclinical challenges in steroid analysis of human samples.Nampt and its potential role in inflammation and type 2 diabetes.Health impact in children and adolescents.Serum visfatin and vaspin levels in prepubertal children: effect of obesity and weight loss after behavior modifications on their secretion and relationship with glucose metabolism.Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trial.Childhood obesity: impact on cardiac geometry and function.Retinol binding protein 4 (RBP4) is primarily associated with adipose tissue mass in children.Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes.NAMPT serum levels are selectively elevated in acute infectious disease and in acute relapse of chronic inflammatory diseases in children.Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies.Heterozygous mutation within a kinase-conserved motif of the insulin-like growth factor I receptor causes intrauterine and postnatal growth retardation.Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children.Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression.Longitudinal multicenter analysis on the course of glucose metabolism in obese children.Sirolimus treatment of severe PTEN hamartoma tumor syndrome: case report and in vitro studies.
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
ricercatrice
@it
հետազոտող
@hy
name
Antje Körner
@ast
Antje Körner
@en
Antje Körner
@es
type
label
Antje Körner
@ast
Antje Körner
@en
Antje Körner
@es
prefLabel
Antje Körner
@ast
Antje Körner
@en
Antje Körner
@es
P214
P1053
B-3988-2015
P106
P1153
8951381400
P21
P214
P31
P3829
P496
0000-0001-6001-0356
P734
P7859
viaf-80759574