Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease.
about
Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's diseasePharmacological characterization of memoquin, a multi-target compound for the treatment of Alzheimer's diseaseMemoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's diseaseAlzPlatform: an Alzheimer's disease domain-specific chemogenomics knowledgebase for polypharmacology and target identification research.The discovery of potential acetylcholinesterase inhibitors: a combination of pharmacophore modeling, virtual screening, and molecular docking studies.Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics.Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.Designing drugs with multi-target activity: the next step in the treatment of neurodegenerative disorders.Huprines for Alzheimer's disease drug development.Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-β aggregation.Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer's Disease.Commonalities in biological pathways, genetics, and cellular mechanism between Alzheimer Disease and other neurodegenerative diseases: An in silico-updated overview.New semicarbazones as gorge-spanning ligands of acetylcholinesterase and potential new drugs against Alzheimer's disease: Synthesis, molecular modeling, NMR, and biological evaluation.The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon.Scale Alpha and Beta of Quantitative Convergence and Chemical Reactivity Analysis in Dual Cholinesterase/Monoamine Oxidase Inhibitors for the Alzheimer Disease Treatment Using Density Functional Theory (DFT)
P2860
Q28287090-4CA4B67A-EF06-428F-ADE3-C5EF262F6E13Q28486236-89A64FF5-4BBE-4621-BAD5-5CE4A82C0A57Q28820783-65450C94-D00E-4AD6-86C3-EC1FF726F871Q33567120-C4AFE94D-1729-4AB9-AD18-18629A198C8BQ34564278-0AE6B410-5B19-4E2C-A9CC-1A6FCC3CCF6CQ36838929-B5C61C37-0E76-4BB6-8626-6086802E4361Q37559812-01F68262-26FB-45A1-ABE9-F1DDB7E41AC7Q38066606-9BDC0878-D3C0-45A1-91B2-A8061B8187FFQ38088283-91BE7DCC-78EB-44E3-B29E-B45F87DF0C03Q38668998-5D6C4776-AE6C-4639-81E9-A4AEB7A6E1C3Q38793949-6CC31F30-6FE5-4354-990D-45C20D01C9DBQ39121710-AB3D6AEB-78AB-4E16-87D7-0AF6438E2B7BQ47290054-8F60B6F1-F2E1-4B89-BA25-93503C48C4F9Q50859830-3439DF18-4220-49E4-B65A-B9662A37668BQ59022312-CE5D60D3-2370-4FF0-9BC1-18551E22EC5E
P2860
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Novel class of quinone-bearing ...... to combat Alzheimer's disease.
@en
type
label
Novel class of quinone-bearing ...... to combat Alzheimer's disease.
@en
prefLabel
Novel class of quinone-bearing ...... to combat Alzheimer's disease.
@en
P2093
P50
P356
P1476
Novel class of quinone-bearing ...... to combat Alzheimer's disease.
@en
P2093
Andrea Cavalli
Andrea Tarozzi
Carlo Melchiorre
Christian Bergamini
Giorgio Lenaz
Maria Laura Bolognesi
Maurizio Recanatini
Michela Rosini
Patrizia Hrelia
Rita Banzi
P304
P356
10.1021/JM070559A
P407
P577
2007-09-13T00:00:00Z