Phenylimidazole derivatives of 4-pyridone as dual inhibitors of bacterial enoyl-acyl carrier protein reductases FabI and FabK.

Phenylimidazole derivatives of 4-pyridone as dual inhibitors of bacterial enoyl-acyl carrier protein reductases FabI and FabK.

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http://www.wikidata.org/entity/Q40090706
Crystal structure of enoyl-acyl carrier protein reductase (FabK) fromStreptococcus pneumoniaereveals the binding mode of an inhibitorDiscovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitorsChallenges of antibacterial discoveryInvestigational antimicrobial agents of 2013.Mutations associated with reduced surotomycin susceptibility in Clostridium difficile and Enterococcus speciesSelectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.Diversity in enoyl-acyl carrier protein reductases.Enoyl acyl carrier protein reductase inhibitors: a patent review (2006 - 2010).Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents.Carbon-carbon double-bond reductases in nature.Studies of Staphylococcus aureus FabI inhibitors: fragment-based approach based on holographic structure-activity relationship analyses.Rational design and synthesis of novel diphenyl ether derivatives as antitubercular agents.An efficient method for the construction of polysubstituted 4-pyridones via self-condensation of β-keto amides mediated by P2O5 and catalyzed by zinc bromide.Design and synthesis of 2-pyridones as novel inhibitors of the Bacillus anthracis enoyl-ACP reductase.Reactions between Grignard reagents and heterocyclic N-oxides: stereoselective synthesis of substituted pyridines, piperidines, and piperazines.Rational questing for potential novel inhibitors of FabK from Streptococcus pneumoniae by combining FMO calculation, CoMFA 3D-QSAR modeling and virtual screening.Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.
P2860

Phenylimidazole derivatives of 4-pyridone as dual inhibitors of bacterial enoyl-acyl carrier protein reductases FabI and FabK.

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http://www.wikidata.org/entity/Q40090706
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Phenylimidazole derivatives of ...... tein reductases FabI and FabK.
@en
type
label
Phenylimidazole derivatives of ...... tein reductases FabI and FabK.
@en
prefLabel
Phenylimidazole derivatives of ...... tein reductases FabI and FabK.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Phenylimidazole derivatives of ...... tein reductases FabI and FabK.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698