Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer.
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ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancerMechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancerAn integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progressionNew strategies in metastatic prostate cancer: targeting the androgen receptor signaling pathwayPrevalence of TMPRSS2-ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohortExome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancerThe genomic complexity of primary human prostate cancerNew tricks from an old oncogene: gene fusion and copy number alterations of MYB in human cancerIdentification of AML1-ETO modulators by chemical genomicsThe role of SPINK1 in ETS rearrangement-negative prostate cancersCharacterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancerIdentification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencingTranscriptome sequencing to detect gene fusions in cancerViruses associated with human cancerChoreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear ArchitectureRecurrent rearrangements in prostate cancer: causes and therapeutic potentialThe mutational landscape of prostate cancerEndogenous retroviruses and the development of cancerBeyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid TumorsGenomic sequencing in cancerAt the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of boneDiscovery and Classification of Fusion Transcripts in Prostate Cancer and Normal Prostate TissueFusion oncogenes in salivary gland tumors: molecular and clinical consequencesHuman endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?Interplay between genomic alterations and androgen receptor signaling during prostate cancer development and progressionThe emergence of lncRNAs in cancer biologyGenetically engineered mouse models of prostate cancerEGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated GenesGenetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse modelsA small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft modelIdentification of targetable FGFR gene fusions in diverse cancers.Integrative clinical genomics of advanced prostate cancer.Endogenous retroviral promoter exaptation in human cancerSnaps and mends: DNA breaks and chromosomal translocationsRole of the TMPRSS2-ERG gene fusion in prostate cancerYK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasionHigh-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancerBreakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer typesEmergence of FGFR family gene fusions as therapeutic targets in a wide spectrum of solid tumoursLINE-1 elements in structural variation and disease
P2860
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P2860
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Distinct classes of chromosoma ...... ne fusions in prostate cancer.
@en
type
label
Distinct classes of chromosoma ...... ne fusions in prostate cancer.
@en
prefLabel
Distinct classes of chromosoma ...... ne fusions in prostate cancer.
@en
P2093
P50
P356
P1433
P1476
Distinct classes of chromosoma ...... ne fusions in prostate cancer.
@en
P2093
Anjana Menon
Arul M Chinnaiyan
Beth E Helgeson
Bharathi Laxman
David S Morris
Diane Roulston
James E Montie
P2888
P304
P356
10.1038/NATURE06024
P407
P577
2007-08-01T00:00:00Z
P5875
P6179
1027447235