Simian virus 40 large T antigen induces or activates a protein kinase which phosphorylates the transformation-associated protein p53.
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Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigenHuman DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.A kinase activity associated with simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivoNuclear protein phosphorylation and growth control.Characterization of human vascular smooth muscle cells transformed by the early genetic region of SV40 virus.Protein phosphatases and DNA tumor viruses: transformation through the back door?Stable T-p53 complexes are not required for replication of simian virus 40 in culture or for enhanced phosphorylation of T antigen and p53.Species-specific phosphorylation of mouse and rat p53 in simian virus 40-transformed cells.Simian virus 40 can overcome the antiproliferative effect of wild-type p53 in the absence of stable large T antigen-p53 binding.Simian virus 40 small t antigen activates the carboxyl-terminal transforming p53-binding domain of large T antigen.Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: influence of viral and cellular factors and biological consequences.Altered phosphorylation of free and bound forms of monkey p53 and simian virus 40 large T antigen during lytic infection.Phenotype-specific phosphorylation of simian virus 40 tsA mutant large T antigens in tsA N-type and A-type transformants.Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: a possible anticancer mechanism.
P2860
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P2860
Simian virus 40 large T antigen induces or activates a protein kinase which phosphorylates the transformation-associated protein p53.
description
1990 nî lūn-bûn
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1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
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1990年学术文章
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1990年学术文章
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1990年学术文章
@zh-sg
1990年學術文章
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1990年學術文章
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1990年學術文章
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name
Simian virus 40 large T antige ...... mation-associated protein p53.
@en
type
label
Simian virus 40 large T antige ...... mation-associated protein p53.
@en
prefLabel
Simian virus 40 large T antige ...... mation-associated protein p53.
@en
P2860
P1433
P1476
Simian virus 40 large T antige ...... mation-associated protein p53.
@en
P2093
K H Scheidtmann
P2860
P304
P407
P577
1990-02-01T00:00:00Z