Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
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Long non-coding RNAs in anti-cancer drug resistanceCrucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2A yeast-based genomic strategy highlights the cell protein networks altered by FTase inhibitor peptidomimeticsAsbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathwaysScreening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interferenceIncreased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells.Biphasic regulation of P-glycoprotein function and expression by NO donors in Caco-2 cells.Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks.The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature.Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cellsDrug resistance in cancer: an overview.FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin--proteasome pathway in cancer cells.Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate.Sandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity.Induction of heme oxygenase-1 by Na+-H+ exchanger 1 protein plays a crucial role in imatinib-resistant chronic myeloid leukemia cells.The impact of insulin on chemotherapeutic sensitivity to 5-fluorouracil in gastric cancer cell lines SGC7901, MKN45 and MKN28.Cholesteryl butyrate solid lipid nanoparticles inhibit the adhesion and migration of colon cancer cells.Cytotoxicity of the Sesquiterpene Lactones Neoambrosin and Damsin from Ambrosia maritima Against Multidrug-Resistant Cancer CellsBRAFV600E induces ABCB1/P-glycoprotein expression and drug resistance in B-cells via AP-1 activation.Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment.A leukotriene B4 receptor-2 is associated with paclitaxel resistance in MCF-7/DOX breast cancer cellsTumor therapy with a urokinase plasminogen activator-activated anthrax lethal toxin alone and in combination with paclitaxel.Combined p21-activated kinase and farnesyltransferase inhibitor treatment exhibits enhanced anti-proliferative activity on melanoma, colon and lung cancer cell lines.Asclepiasterol, a novel C21 steroidal glycoside derived from Asclepias curassavica, reverses tumor multidrug resistance by down-regulating P-glycoprotein expression.MEK inhibition leads to lysosome-mediated Na+/I- symporter protein degradation in human breast cancer cells.Triptolide exerts pro-apoptotic and cell cycle arrest activity on drug-resistant human lung cancer A549/Taxol cells via modulation of MAPK and PI3K/Akt signaling pathways.Novel mitogen-activated protein kinase kinase inhibitors.Systems biology approaches to adverse drug effects: the example of cardio-oncology.MicroRNA‑197 reverses the drug resistance of fluorouracil‑induced SGC7901 cells by targeting mitogen‑activated protein kinase 1Upregulation of P-glycoprotein expression by ophthalmic drugs in different corneal in-vitro models.Differential cell growth/apoptosis behavior of 13-hydroxyoctadecadienoic acid enantiomers in a colorectal cancer cell line.Apoptotic cascade inspired lipid nanovesicles show synergism with encapsulated paclitaxel in chemoresistant colon carcinoma.Involvement of CUL4A in regulation of multidrug resistance to P-gp substrate drugs in breast cancer cells.Inhibition of p38 MAPK diminishes doxorubicin-induced drug resistance associated with P-glycoprotein in human leukemia K562 cells.Involvement of the epidermal growth factor receptor in the modulation of multidrug resistance in human hepatocellular carcinoma cells in vitroBlocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin.H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein.Modulation of P-gp expression by lapatinib.Down-regulation of extracellular signal-regulated kinase 1/2 activity in P-glycoprotein-mediated multidrug resistant hepatocellular carcinoma cells.
P2860
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P2860
Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Inhibition of the mitogen-acti ...... -regulation of P-glycoprotein.
@en
type
label
Inhibition of the mitogen-acti ...... -regulation of P-glycoprotein.
@en
prefLabel
Inhibition of the mitogen-acti ...... -regulation of P-glycoprotein.
@en
P2093
P1476
Inhibition of the mitogen-acti ...... -regulation of P-glycoprotein.
@en
P2093
Junko Mitsuhashi
Kazuhiro Katayama
Satomi Tsukahara
Sho Yoshioka
Yoshikazu Sugimoto
P304
P356
10.1158/1535-7163.MCT-07-0148
P577
2007-07-01T00:00:00Z